SULT4A1 Antibody (B-3): sc-374545
- SULT4A1 Antibody (B-3) is a mouse monoclonal IgG1 κ SULT4A1 antibody, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 11-43 near the N-terminus of SULT4A1 of human origin
- SULT4A1 Antibody (B-3) is recommended for detection of SULT4A1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine and porcine
- Anti-SULT4A1 Antibody (B-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SULT4A1 Antibody (B-3) for WB applications. These reagents are now offered in bundles with SULT4A1 Antibody (B-3) (see ordering information below).
SULT4A1 Antibody (B-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects SULT4A1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SULT4A1 (B-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SULT4A1, also known as sulfotransferase family 4A, member 1, plays a crucial role in the sulfation process, which is vital for increasing the water solubility of numerous compounds, thereby facilitating their renal excretion and contributing to the formation of active metabolites. SULT4A1 is primarily localized in the cytoplasm and is highly expressed in the cerebral cortex and frontal lobe, with lower levels found in the cerebellum and other brain regions. SULT4A1 is involved in the elimination of xenobiotics, the activation of procarcinogens, and the regulation of hormones, making SULT4A1 significant in pharmacology and toxicology. Notably, the gene encoding SULT4A1 is located on human chromosome 22q13.2, a region associated with a predisposition to schizophrenia, highlighting SULT4A1′s potential relevance in neuropsychiatric disorders. Additionally, two isoforms of SULT4A1 arise from alternative splicing, which may contribute to SULT4A1′s functional diversity.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
SULT4A1 Antibody (B-3) References:
- Sulfotransferases: genetics and role in toxicology. | Glatt, H., et al. 2000. Toxicol Lett. 112-113: 341-8. PMID: 10720750
- Sulfotransferases in the bioactivation of xenobiotics. | Glatt, H. 2000. Chem Biol Interact. 129: 141-70. PMID: 11154739
- Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects. | Glatt, H., et al. 2001. Mutat Res. 482: 27-40. PMID: 11535246
- Localization of a brain sulfotransferase, SULT4A1, in the human and rat brain: an immunohistochemical study. | Liyou, NE., et al. 2003. J Histochem Cytochem. 51: 1655-64. PMID: 14623933
- Transmission disequilibrium suggests a role for the sulfotransferase-4A1 gene in schizophrenia. | Brennan, MD. and Condra, J. 2005. Am J Med Genet B Neuropsychiatr Genet. 139B: 69-72. PMID: 16152568
- Structural and chemical profiling of the human cytosolic sulfotransferases. | Allali-Hassani, A., et al. 2007. PLoS Biol. 5: e97. PMID: 17425406
- Association of Sult4A1 SNPs with psychopathology and cognition in patients with schizophrenia or schizoaffective disorder. | Meltzer, HY., et al. 2008. Schizophr Res. 106: 258-64. PMID: 18823757
- Lack of exonic sulfotransferase 4A1 mutations in controls and schizophrenia cases. | Lewis, AG. and Minchin, RF. 2009. Psychiatr Genet. 19: 53-5. PMID: 19125109
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SULT4A1 Antibody (B-3) | sc-374545 | 200 µg/ml | $316.00 | |||
SULT4A1 Antibody (B-3): m-IgG Fc BP-HRP Bundle | sc-529768 | 200 µg Ab; 10 µg BP | $354.00 | |||
SULT4A1 Antibody (B-3): m-IgGκ BP-HRP Bundle | sc-522774 | 200 µg Ab, 40 µg BP | $354.00 | |||
SULT4A1 Antibody (B-3): m-IgG1 BP-HRP Bundle | sc-543679 | 200 µg Ab; 20 µg BP | $354.00 | |||
SULT4A1 Antibody (B-3) AC | sc-374545 AC | 500 µg/ml, 25% agarose | $416.00 | |||
SULT4A1 Antibody (B-3) HRP | sc-374545 HRP | 200 µg/ml | $316.00 | |||
SULT4A1 Antibody (B-3) FITC | sc-374545 FITC | 200 µg/ml | $330.00 | |||
SULT4A1 Antibody (B-3) PE | sc-374545 PE | 200 µg/ml | $343.00 | |||
SULT4A1 Antibody (B-3) Alexa Fluor® 488 | sc-374545 AF488 | 200 µg/ml | $357.00 | |||
SULT4A1 Antibody (B-3) Alexa Fluor® 546 | sc-374545 AF546 | 200 µg/ml | $357.00 | |||
SULT4A1 Antibody (B-3) Alexa Fluor® 594 | sc-374545 AF594 | 200 µg/ml | $357.00 | |||
SULT4A1 Antibody (B-3) Alexa Fluor® 647 | sc-374545 AF647 | 200 µg/ml | $357.00 | |||
SULT4A1 Antibody (B-3) Alexa Fluor® 680 | sc-374545 AF680 | 200 µg/ml | $357.00 | |||
SULT4A1 Antibody (B-3) Alexa Fluor® 790 | sc-374545 AF790 | 200 µg/ml | $357.00 | |||
SULT4A1 (B-3) Neutralizing Peptide | sc-374545 P | 100 µg/0.5 ml | $68.00 |