SULT2A1 Antibody (E-7): sc-166108
- SULT2A1 Antibody (E-7) is a mouse monoclonal IgG1 κ SULT2A1 antibody provided at 200 µg/ml
- raised against amino acids 1-285 representing full length SULT2A1 of human origin
- SULT2A1 Antibody (E-7) is recommended for detection of SULT2A1 of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-SULT2A1 Antibody (E-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for SULT2A1 Antibody (E-7) for WB and IHC(P) applications. These reagents are now offered in bundles with SULT2A1 Antibody (E-7) (see ordering information below).
SULT2A1 Antibody (E-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects SULT2A1 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-SULT2A1 antibody (E-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SULT2A1 plays a crucial role in the sulfonation of various substrates, including procarcinogenic xenobiotics, hydroxysteroids, and bile acids, which is essential for detoxification processes in the liver and adrenal tissues. SULT2A1 is particularly important for maintaining hepatic cholesterol homeostasis, as SULT2A1 regulates the metabolism of cholesterol and steroid hormones. SULT2A1 is highly expressed in the liver and adrenal glands, where SULT2A1 contributes to the elimination of potentially harmful compounds and the regulation of steroid hormone levels. Additionally, SULT2A1 interacts with other sulfotransferases, which can influence SULT2A1′s activity and substrate specificity, highlighting the complexity of its role in metabolic pathways.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
SULT2A1 Antibody (E-7) References:
- Sulfotransferase catalyzing sulfation of heterocyclic amines. | Yamazoe, Y., et al. 1999. Cancer Lett. 143: 103-7. PMID: 10503886
- Expression and characterization of the human 3 beta-hydroxysteroid sulfotransferases (SULT2B1a and SULT2B1b). | Meloche, CA. and Falany, CN. 2001. J Steroid Biochem Mol Biol. 77: 261-9. PMID: 11457664
- Structure and localization of the human SULT1B1 gene: neighborhood to SULT1E1 and a SULT1D pseudogene. | Meinl, W. and Glatt, H. 2001. Biochem Biophys Res Commun. 288: 855-62. PMID: 11688987
- Different subcellular localization of sulphotransferase 2B1b in human placenta and prostate. | He, D., et al. 2004. Biochem J. 379: 533-40. PMID: 14741047
- Steroid sulfotransferase 2A1 gene transcription is regulated by steroidogenic factor 1 and GATA-6 in the human adrenal. | Saner, KJ., et al. 2005. Mol Endocrinol. 19: 184-97. PMID: 15388788
- Regulation of human hepatic hydroxysteroid sulfotransferase gene expression by the peroxisome proliferator-activated receptor alpha transcription factor. | Fang, HL., et al. 2005. Mol Pharmacol. 67: 1257-67. PMID: 15635043
- Identification and immunohistochemical localization of Sulfotransferase 2B1b (SULT2B1b) in human lung. | He, D., et al. 2005. Biochim Biophys Acta. 1724: 119-26. PMID: 15878639
- Arylamine activating sulfotransferase in liver. | Nagata, K., et al. 1997. Mutat Res. 376: 267-72. PMID: 9202764
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SULT2A1 Antibody (E-7) | sc-166108 | 200 µg/ml | $316.00 | |||
SULT2A1 Antibody (E-7): m-IgG Fc BP-HRP Bundle | sc-527136 | 200 µg Ab; 10 µg BP | $354.00 | |||
SULT2A1 Antibody (E-7): m-IgG1 BP-HRP Bundle | sc-532509 | 200 µg Ab; 20 µg BP | $354.00 | |||
SULT2A1 Antibody (E-7) AC | sc-166108 AC | 500 µg/ml, 25% agarose | $416.00 | |||
SULT2A1 Antibody (E-7) HRP | sc-166108 HRP | 200 µg/ml | $316.00 | |||
SULT2A1 Antibody (E-7) FITC | sc-166108 FITC | 200 µg/ml | $330.00 | |||
SULT2A1 Antibody (E-7) PE | sc-166108 PE | 200 µg/ml | $343.00 | |||
SULT2A1 Antibody (E-7) Alexa Fluor® 488 | sc-166108 AF488 | 200 µg/ml | $357.00 | |||
SULT2A1 Antibody (E-7) Alexa Fluor® 546 | sc-166108 AF546 | 200 µg/ml | $357.00 | |||
SULT2A1 Antibody (E-7) Alexa Fluor® 594 | sc-166108 AF594 | 200 µg/ml | $357.00 | |||
SULT2A1 Antibody (E-7) Alexa Fluor® 647 | sc-166108 AF647 | 200 µg/ml | $357.00 | |||
SULT2A1 Antibody (E-7) Alexa Fluor® 680 | sc-166108 AF680 | 200 µg/ml | $357.00 | |||
SULT2A1 Antibody (E-7) Alexa Fluor® 790 | sc-166108 AF790 | 200 µg/ml | $357.00 |