STOP Antibody (B-1): sc-133223
- STOP Antibody (B-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of STOP of mouse origin
- recommended for detection of STOP of mouse and rat origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for STOP Antibody (B-1) for WB applications. These reagents are now offered in bundles with STOP Antibody (B-1) (see ordering information below).
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SEE ALSO...
STOP Antibody (B-1) is a mouse monoclonal IgG1 antibody that detects STOP in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-STOP antibody (B-1) plays a crucial role in studying microtubule stability, particularly in neuronal cells, where STOP is essential for maintaining microtubule integrity under adverse conditions. STOP, consisting of 952 amino acids, is characterized by a unique structure, which includes five tandem repeats of 46 amino acids in its central region and a SH3-binding motif near its N-terminus. This structural configuration facilitates STOP′s interaction with other cellular components, thereby enhancing microtubule stability in the axon and cell body, even at extremely low temperatures, such as -80° C. STOP′s ability to confer cold stability to microtubules is particularly important for understanding neuronal resilience and mechanisms underlying neurodegenerative diseases, making anti-STOP antibody (B-1) an invaluable tool for researchers investigating these critical biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
STOP Antibody (B-1) | sc-133223 | 200 µg/ml | $322.00 | |||
STOP Antibody (B-1): m-IgG Fc BP-HRP Bundle | sc-539869 | 200 µg Ab; 10 µg BP | $361.00 | |||
STOP Antibody (B-1): m-IgG1 BP-HRP Bundle | sc-541755 | 200 µg Ab; 20 µg BP | $361.00 |