STOML2 Antibody (C-3): sc-376165
- STOML2 Antibody (C-3) is a mouse monoclonal IgG2a κ STOML2 antibody, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 177-356 mapping at the C-terminus of STOML2 of human origin
- STOML2 Antibody (C-3) is recommended for detection of STOML2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-STOML2 Antibody (C-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for STOML2 Antibody (C-3) for WB and IHC(P) applications. These reagents are now offered in bundles with STOML2 Antibody (C-3) (see ordering information below).
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STOML2 Antibody (C-3) is a mouse monoclonal IgG2a kappa light chain antibody that detects STOML2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). STOML2 (C-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Stomatin-like protein 2 (STOML2), also known as SLP-2 or EPB72-like 2, is a 356 amino acid protein that belongs to the mec-2 family and is expressed at low levels across various tissues, with particularly high expression in heart, liver, and pancreas. STOML2 is primarily localized in the cytoplasm, with some presence on the membrane, which is crucial for regulating ion channel conductances and organizing lipid rafts rich in sphingolipids and cholesterol. These lipid rafts are essential for various cellular processes, including signal transduction and membrane trafficking, highlighting STOML2′s importance in maintaining cellular homeostasis and potentially influencing tumorigenesis, as STOML2 was first identified as an overexpressed protein in human endometrial adenocarcinoma. Changes in cell growth associated with varying levels of STOML2 suggest involvement in endometrial tumorigenesis, making STOML2 a significant target for further research in cancer biology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
STOML2 Antibody (C-3) References:
- Identification and characterization of human SLP-2, a novel homologue of stomatin (band 7.2b) present in erythrocytes and other tissues. | Wang, Y. and Morrow, JS. 2000. J Biol Chem. 275: 8062-71. PMID: 10713127
- A novel member of the STOMATIN/EPB72/mec-2 family, stomatin-like 2 (STOML2), is ubiquitously expressed and localizes to HSA chromosome 9p13.1. | Owczarek, CM., et al. 2001. Cytogenet Cell Genet. 92: 196-203. PMID: 11435687
- [Effect of stomatin-like protein 2 (SLP-2) gene on growth and proliferation of esophageal squamous carcinoma cell line TE12]. | Zhang, LY., et al. 2005. Ai Zheng. 24: 155-9. PMID: 15694024
- Stomatin-like protein 2 is overexpressed in cancer and involved in regulating cell growth and cell adhesion in human esophageal squamous cell carcinoma. | Zhang, L., et al. 2006. Clin Cancer Res. 12: 1639-46. PMID: 16533792
- Mass spectrometrical verification of stomatin-like protein 2 (SLP-2) primary structure. | John, JP., et al. 2006. Proteins. 64: 543-51. PMID: 16671055
- Identification of a novel mitochondrial complex containing mitofusin 2 and stomatin-like protein 2. | Hájek, P., et al. 2007. J Biol Chem. 282: 5670-81. PMID: 17121834
- Prognostic significance of stomatin-like protein 2 overexpression in laryngeal squamous cell carcinoma: clinical, histologic, and immunohistochemistry analyses with tissue microarray. | Cao, WF., et al. 2007. Hum Pathol. 38: 747-52. PMID: 17306333
- Stomatin-like protein 2 is overexpressed and related to cell growth in human endometrial adenocarcinoma. | Cui, Z., et al. 2007. Oncol Rep. 17: 829-33. PMID: 17342323
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
STOML2 Antibody (C-3) | sc-376165 | 200 µg/ml | $322.00 | |||
STOML2 Antibody (C-3): m-IgG Fc BP-HRP Bundle | sc-529828 | 200 µg Ab; 10 µg BP | $361.00 | |||
STOML2 Antibody (C-3): m-IgGκ BP-HRP Bundle | sc-522858 | 200 µg Ab, 40 µg BP | $361.00 | |||
STOML2 Antibody (C-3): m-IgG2a BP-HRP Bundle | sc-547387 | 200 µg Ab; 10 µg BP | $361.00 | |||
STOML2 Antibody (C-3) AC | sc-376165 AC | 500 µg/ml, 25% agarose | $424.00 | |||
STOML2 Antibody (C-3) HRP | sc-376165 HRP | 200 µg/ml | $322.00 | |||
STOML2 Antibody (C-3) FITC | sc-376165 FITC | 200 µg/ml | $336.00 | |||
STOML2 Antibody (C-3) PE | sc-376165 PE | 200 µg/ml | $349.00 | |||
STOML2 Antibody (C-3) Alexa Fluor® 488 | sc-376165 AF488 | 200 µg/ml | $364.00 | |||
STOML2 Antibody (C-3) Alexa Fluor® 546 | sc-376165 AF546 | 200 µg/ml | $364.00 | |||
STOML2 Antibody (C-3) Alexa Fluor® 594 | sc-376165 AF594 | 200 µg/ml | $364.00 | |||
STOML2 Antibody (C-3) Alexa Fluor® 647 | sc-376165 AF647 | 200 µg/ml | $364.00 | |||
STOML2 Antibody (C-3) Alexa Fluor® 680 | sc-376165 AF680 | 200 µg/ml | $364.00 | |||
STOML2 Antibody (C-3) Alexa Fluor® 790 | sc-376165 AF790 | 200 µg/ml | $364.00 |