Stat4 Antibody (PL68): sc-101160
- Stat4 Antibody (PL68) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 100 µg/ml
- raised against recombinant Stat4 of human origin
- recommended for detection of Stat4 of human origin by WB, IP, IF, IHC(P) and ELISA
- See Stat4 (C-4): sc-398228 for Stat4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Stat4 Antibody (PL68). This work is in progress.
Stat4 Antibody (PL68) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect Signal Transducer and Activator of Transcription 4 (Stat4), a crucial member of the STAT family involved in cytokine signaling and immune response regulation. Anti-Stat4 antibody (PL68) is raised against recombinant human Stat4 and is validated for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA), specifically recognizing Stat4 from human origin. Stat4, also known as STAT4, is primarily located in the cytoplasm and translocates to the nucleus upon activation by cytokines such as interleukin-12 (IL-12), where Stat4 functions as a transcription factor to regulate gene expression. This nuclear localization is essential for promoting the differentiation of naive T cells into Th1 cells, which are vital for orchestrating the body′s immune response against intracellular pathogens and in the development of autoimmune diseases. By mediating responses to cytokines, Stat4 plays a significant role in the regulation of inflammation, hematopoiesis, and the immune system′s ability to respond to infections. Stat4 monoclonal antibody (PL68) is an indispensable tool for researchers studying the molecular mechanisms underlying immune cell differentiation, inflammatory pathways, and cytokine signaling. Anti-Stat4 antibody (PL68) enables accurate detection and analysis of Stat4 in various experimental settings, facilitating advancements in immunology and related biomedical fields.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Stat4 Antibody (PL68) | sc-101160 | 100 µg/ml | $339.00 |