Staphylococcus aureus Antibody (702): sc-58036

Staphylococcus aureus Antibody (702) is a mouse monoclonal IgG3 antibody that detects Staphylococcus aureus through enzyme-linked immunosorbent assay (ELISA) with non-species reactivity. Staphylococcus aureus is a Gram-positive coccus that commonly resides on human skin and in nasal passages, where Staphylococcus aureus can exist harmlessly but also has potential to cause infections ranging from minor skin issues to severe conditions like pneumonia and septicemia. Staphylococcus aureus produces β-lactamase, an enzyme degrading the β-lactam ring of penicillin, creating resistance to many antibiotics, including penicillin and cephalosporins. This resistance complicates treatment options for infections in clinical settings. Staphylococcus aureus produces Toxic Shock Syndrome Toxin-1 (TSST-1), a potent exotoxin causing life-threatening conditions through nonspecific binding of major histocompatibility complex class II molecules with T cell receptors, resulting in widespread T cell activation. TSST-1′s activity extends beyond acute infections, contributing to autoimmune and allergic diseases through B cell hyperactivity and antagonistic effects on interleukin-4-induced immunoglobulin E synthesis. Toxic shock syndrome symptoms from TSST-1 include high fever, hypotension, and confusion, potentially leading to severe complications like multi-organ failure. Staphylococcus aureus (702) monoclonal antibody serves as an essential tool for studying pathogenic mechanisms of this bacterium and associated diseases.

The preferred Staphylococcus aureus antibody is Staphylococcus aureus Antibody (704): sc-58038.