SPCA2 Antibody (C-9): sc-376917
- SPCA2 Antibody (C-9) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 397-439 mapping within an internal region of SPCA2 of human origin
- recommended for detection of SPCA2 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for SPCA2 Antibody (C-9) for WB applications. This reagent is now offered in a bundle with SPCA2 Antibody (C-9) (see ordering information below).
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SPCA2 Antibody (C-9) is a mouse monoclonal IgG1 antibody that detects SPCA2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SPCA2, encoded by the ATP2C2 gene, is a Ca2+/Mn2+-transport ATPase that plays a crucial role in maintaining calcium homeostasis within secretory cells. SPCA2 is primarily localized to the Golgi apparatus, where SPCA2 is essential for regulating the ionic environment necessary for proper protein processing and secretion. The Golgi apparatus is a critical hub for post-translational modifications and sorting of proteins, and SPCA2 activity ensures that calcium levels are finely tuned to facilitate these processes. Notably, SPCA2 exhibits a higher enzymatic turnover rate compared to SPCA1, which allows rapid response to changes in cellular calcium demands, particularly in tissues such as the gastrointestinal and respiratory tracts, prostate, thyroid, salivary, and mammary glands. The specific physiological role of SPCA2 in these secretory cells underscores SPCA2′s importance in various biological functions, making anti-SPCA2 antibody (C-9) a valuable tool for researchers studying calcium transport and cellular physiology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SPCA2 Antibody (C-9) | sc-376917 | 200 µg/ml | $316.00 | |||
SPCA2 Antibody (C-9): m-IgG Fc BP-HRP Bundle | sc-540666 | 200 µg Ab; 10 µg BP | $354.00 |