Date published: 2025-12-8

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SPCA Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of SPCA Antibodies for advanced research in cellular and molecular biology. SPCA Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SPCA, or Secretory Pathway Calcium ATPase, plays a crucial role in calcium homeostasis and is essential for various cellular processes, including muscle contraction, neurotransmitter release, and cell signaling. The proper functioning of SPCA is vital for maintaining cellular health and preventing diseases related to calcium dysregulation. Researchers studying SPCA can investigate calcium transport mechanisms across different cell types and tissues. Understanding SPCA function helps illuminate potential therapeutic targets for diseases involving calcium imbalances. Advanced detection methods using specific conjugates such as horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC) enable precise visualization of SPCA localization and activity. Santa Cruz Biotechnology monoclonal antibodies for SPCA research support scientists worldwide in advancing our understanding of calcium-dependent cellular processes and disease mechanisms.

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SPCA Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SPCA1/2 Antibody (B-3)

sc-377339mouse IgG2a κ711-820 (h)WB, IP, IF, ELISAh

new

(1)

SPCA2 Antibody (B-5)

sc-398330mouse IgG1925-946 (h)WB, IP, IF, ELISAh

new

(3)

SPCA2 Antibody (C-9)

sc-376917mouse IgG1 κ397-439 (h)WB, IP, IF, ELISAh

new

(1)

SPCA CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPCA2 CRISPR/Cas9 KO Plasmid (h)

sc-405056hGene KnockoutGFP0
(0)

SPCA2 HDR Plasmid (h)

sc-405056-HDRhHomology Directed RepairPuromycin0
(0)

SPCA2 Double Nickase Plasmid (h)

sc-405056-NIChGene KnockoutPuromycin0
(0)

SPCA2 Double Nickase Plasmid (h2)

sc-405056-NIC-2hGene KnockoutPuromycin0
(0)

SPCA2 CRISPR/Cas9 KO Plasmid (m)

sc-427273mGene KnockoutGFP0
(0)

SPCA2 HDR Plasmid (m)

sc-427273-HDRmHomology Directed RepairPuromycin0
(0)

SPCA2 Double Nickase Plasmid (m)

sc-427273-NICmGene KnockoutPuromycin0
(0)

SPCA2 Double Nickase Plasmid (m2)

sc-427273-NIC-2mGene KnockoutPuromycin0
(0)

SPCA CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPCA2 CRISPR Activation Plasmid (h)

sc-405056-ACThGene ActivationPuro, Blast, Hygro0
(0)

SPCA2 CRISPR Activation Plasmid (h2)

sc-405056-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SPCA2 Lentiviral Activation Particles (h)

sc-405056-LAChGene ActivationPuro, Blast, Hygro0
(0)

SPCA2 Lentiviral Activation Particles (h2)

sc-405056-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SPCA2 CRISPR Activation Plasmid (m)

sc-427273-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SPCA2 CRISPR Activation Plasmid (m2)

sc-427273-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SPCA2 Lentiviral Activation Particles (m)

sc-427273-LACmGene ActivationPuro, Blast, Hygro0
(0)

SPCA2 Lentiviral Activation Particles (m2)

sc-427273-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SPCA siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPCA2 siRNA (h)

sc-61605hGene SilencingN/A0
(0)

SPCA2 shRNA Plasmid (h)

sc-61605-SHhGene SilencingPuromycin0
(0)

SPCA2 shRNA (h) Lentiviral Particles

sc-61605-VhGene SilencingPuromycin0
(0)

SPCA2 siRNA (m)

sc-153730mGene SilencingN/A0
(0)

SPCA2 shRNA Plasmid (m)

sc-153730-SHmGene SilencingPuromycin0
(0)

SPCA2 shRNA (m) Lentiviral Particles

sc-153730-VmGene SilencingPuromycin0
(0)