Sox2 Antibody (A-5): sc-365964
- Sox2 Antibody (A-5) is a mouse monoclonal IgG2a κ, cited in 48 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 170-201 within an internal region of Sox-2 of human origin
- Anti-Sox2 Antibody (A-5) is recommended for detection of Sox-2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine and bovine
- TransCruz reagent for ChIP application (sc-365964 X, 200 µg/0.1 ml)
- Anti-Sox2 Antibody (A-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for Sox2 Antibody (A-5) for WB and IHC(P) applications. These reagents are now offered in bundles with Sox2 Antibody (A-5) (see ordering information below).
Sox-2 Antibody (A-5) is a mouse monoclonal IgG2a kappa light chain antibody engineered to detect human Sox-2 protein with exceptional accuracy in a variety of applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Sox-2 monoclonal antibody (A-5) targets a precisely mapped epitope within amino acids 170-201 of the internal region of human Sox-2, ensuring strong and reliable binding. Anti-Sox-2 antibody (A-5) exhibits broad species reactivity, effectively recognizing Sox-2 from mouse, rat, and human origins, as well as other species such as equine, canine, and bovine, making Sox-2 (A-5) antibody a versatile tool for diverse research needs. Sox-2, also referred to as lcc, ysb, and Sox2, is a critical member of the SRY-related HMG-box (Sox) family of transcription factors, characterized by the presence of a High-Mobility Group (HMG) domain that facilitates sequence-specific DNA binding and induces conformational changes in DNA structure. This structural feature is essential for Sox-2′s role in bending DNA, thereby regulating the transcription of target genes involved in maintaining pluripotency and self-renewal in embryonic stem cells. The HMG domain allows Sox-2 to interact with other transcription factors and co-regulators, orchestrating complex gene expression programs that dictate cell fate decisions and drive key developmental processes. Understanding Sox-2′s structural dynamics is crucial, as mutations can lead to various developmental disorders and have been implicated in oncogenesis, highlighting Sox-2′s significance in both normal physiological functions and pathological conditions. Sox-2 (A-5) monoclonal antibody is available in both non-conjugated form and multiple conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates, providing flexibility and convenience for a wide range of experimental applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sox2 Antibody (A-5) | sc-365964 | 200 µg/ml | $316.00 | |||
Sox2 Antibody (A-5): m-IgG Fc BP-HRP Bundle | sc-525909 | 200 µg Ab; 10 µg BP | $354.00 | |||
Sox2 Antibody (A-5): m-IgG2a BP-HRP Bundle | sc-546456 | 200 µg Ab; 10 µg BP | $354.00 | |||
Sox2 Antibody (A-5) X | sc-365964 X | 200 µg/0.1 ml | $316.00 | |||
Sox2 Antibody (A-5) AC | sc-365964 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Sox2 Antibody (A-5) HRP | sc-365964 HRP | 200 µg/ml | $316.00 | |||
Sox2 Antibody (A-5) FITC | sc-365964 FITC | 200 µg/ml | $330.00 | |||
Sox2 Antibody (A-5) PE | sc-365964 PE | 200 µg/ml | $343.00 | |||
Sox2 Antibody (A-5) Alexa Fluor® 488 | sc-365964 AF488 | 200 µg/ml | $357.00 | |||
Sox2 Antibody (A-5) Alexa Fluor® 546 | sc-365964 AF546 | 200 µg/ml | $357.00 | |||
Sox2 Antibody (A-5) Alexa Fluor® 594 | sc-365964 AF594 | 200 µg/ml | $357.00 | |||
Sox2 Antibody (A-5) Alexa Fluor® 647 | sc-365964 AF647 | 200 µg/ml | $357.00 | |||
Sox2 Antibody (A-5) Alexa Fluor® 680 | sc-365964 AF680 | 200 µg/ml | $357.00 | |||
Sox2 Antibody (A-5) Alexa Fluor® 790 | sc-365964 AF790 | 200 µg/ml | $357.00 | |||
Sox2 (A-5) Neutralizing Peptide | sc-365964 P | 100 µg/0.5 ml | $68.00 |