SNX17 Antibody (D-10): sc-166585
- SNX17 Antibody (D-10) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 82-101 near the N-terminus of SNX17 of human origin
- recommended for detection of SNX17 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine and bovine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for SNX17 Antibody (D-10) for WB applications. These reagents are now offered in bundles with SNX17 Antibody (D-10) (see ordering information below).
SNX17 Antibody (D-10) is a mouse monoclonal IgG1 antibody that detects SNX17 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SNX17 is a crucial component of the cellular sorting machinery, playing a significant role in regulating cell surface levels of lipoprotein receptor-related protein (LRP) by facilitating recycling. SNX17 is characterized by a unique phox homology (PX) domain, which interacts with phosphatidylinositol-3-phosphate, allowing SNX17 to associate with membranes effectively. SNX17 contains a FERM domain and a carboxyl-terminal region that are essential for binding to LRP, highlighting SNX17′s importance in intracellular trafficking and receptor regulation. Research has shown that SNX17 is predominantly localized to the limiting membrane and recycling tubules of early endosomes, underscoring SNX17′s vital role in maintaining cellular homeostasis and signaling pathways. Anti-SNX17 antibody (D-10) is an invaluable tool for researchers studying the dynamics of receptor recycling and intracellular transport mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SNX17 Antibody (D-10) | sc-166585 | 200 µg/ml | $316.00 | |||
SNX17 Antibody (D-10): m-IgG Fc BP-HRP Bundle | sc-540125 | 200 µg Ab; 10 µg BP | $354.00 | |||
SNX17 Antibody (D-10): m-IgG1 BP-HRP Bundle | sc-541919 | 200 µg Ab; 20 µg BP | $354.00 | |||
SNX17 (D-10) Neutralizing Peptide | sc-166585 P | 100 µg/0.5 ml | $68.00 |