SNAT4 Antibody (A-4): sc-514047

SNAT4 Antibody (A-4) is a mouse monoclonal IgG2a antibody that detects SNAT4 in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SNAT4, also known as ATA3, NAT3, or PAAT, is a member of the sodium-coupled neutral amino acid transporter family, specifically the SLC38 gene family, and plays a crucial role in the transport of neutral amino acids across cell membranes. SNAT4 is predominantly expressed in the liver during both embryonic and adult stages, with lesser expression observed in muscle, kidney, and pancreas tissues. SNAT4 localization in the liver is particularly significant as SNAT4 is essential for nutrient uptake, energy production, and metabolic processes, which are vital for maintaining overall cellular function and homeostasis. Furthermore, SNAT4 activity is linked to fetal development, and disruptions in SNAT4 transport function have been associated with fetal growth retardation, highlighting SNAT4 importance in developmental biology. anti-SNAT4 antibody (A-4) is an invaluable tool for researchers studying amino acid transport mechanisms and their implications in health and disease.

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SNAT4 Antibody (A-4) References:

1. Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family.  |  Mackenzie, B. and Erickson, JD. 2004. Pflugers Arch. 447: 784-95. PMID: 12845534
2. Membrane topological structure of neutral system N/A amino acid transporter 4 (SNAT4) protein.  |  Shi, Q., et al. 2011. J Biol Chem. 286: 38086-38094. PMID: 21917917
3. Association of SLC38A4 and system A with abnormal fetal birth weight.  |  Li, Z., et al. 2012. Exp Ther Med. 3: 309-313. PMID: 22969887
4. Sodium-coupled neutral amino acid transporter 4 functions as a regulator of protein synthesis during liver development.  |  Kondou, H., et al. 2013. Hepatol Res. 43: 1211-23. PMID: 23607685
5. System A amino acid transporter SNAT2 shows subtype-specific affinity for betaine and hyperosmotic inducibility in placental trophoblasts.  |  Nishimura, T., et al. 2014. Biochim Biophys Acta. 1838: 1306-12. PMID: 24434061
6. Pre-targeted Imaging of Protease Activity through In Situ Assembly of Nanoparticles.  |  Chen, Z., et al. 2020. Angew Chem Int Ed Engl. 59: 7864-7870. PMID: 32056345
7. A GC-MS/Single-Cell Method to Evaluate Membrane Transporter Substrate Specificity and Signaling.  |  Fairweather, SJ., et al. 2021. Front Mol Biosci. 8: 646574. PMID: 33928121
8. Evaluation of a procaspase-3 activator with hydroxyurea or temozolomide against high-grade meningioma in cell culture and canine cancer patients.  |  Tonogai, EJ., et al. 2021. Neuro Oncol. 23: 1723-1735. PMID: 34216463
9. Placental Nutrient Transporters and Maternal Fatty Acids in SGA, AGA, and LGA Newborns From Mothers With and Without Obesity.  |  Garcia-Santillan, JA., et al. 2022. Front Cell Dev Biol. 10: 822527. PMID: 35399516
10. Platelets Affect the Activity of Amino Acid Transporter SNAT4 in HuH-7 Human Hepatoma Cells.  |  Kashiwagi, H., et al. 2024. Biol Pharm Bull. 47: 652-659. PMID: 38508745

The preferred SNAT4 antibody is SNAT4 Antibody (H-9): sc-376664.