SNAP 29 Antibody (E-5): sc-390602
- SNAP 29 Antibody (E-5) is a mouse monoclonal IgG1 κ SNAP 29 antibody, cited in 6 publications, provided at 200 µg/ml
- raised against amino acids 1-258 representing full length SNAP 29 of human origin
- SNAP 29 Antibody (E-5) is recommended for detection of SNAP 29 of human origin by WB, IP, IF and ELISA
- Anti-SNAP 29 Antibody (E-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SNAP 29 Antibody (E-5). This work is in progress.
SNAP 29 Antibody (E-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects SNAP 29 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-SNAP 29 antibody (E-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SNAP 29 plays a crucial role in regulating membrane trafficking and exocytosis, which are essential processes for neurotransmitter release and cellular communication. Located primarily on cytoplasmic surfaces of cellular membranes, SNAP 29 interacts with several key proteins involved in these processes, including vesicle-associated membrane proteins (VAMPs) and soluble NSF attachment proteins (SNAPs). Such interaction is vital for forming the SNARE complex, which facilitates vesicle fusion with target membranes, thereby ensuring proper release of neurotransmitters and other signaling molecules. SNAP 29′s ability to anchor to membranes and bind to these proteins underscores its importance in maintaining cellular homeostasis and effective communication between cells.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
SNAP 29 Antibody (E-5) References:
- The syntaxin family of vesicular transport receptors. | Bennett, MK., et al. 1993. Cell. 74: 863-73. PMID: 7690687
- Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine. | Edelmann, L., et al. 1995. EMBO J. 14: 224-31. PMID: 7835333
- Synaptic core complex of synaptobrevin, syntaxin, and SNAP25 forms high affinity alpha-SNAP binding site. | McMahon, HT. and Südhof, TC. 1995. J Biol Chem. 270: 2213-7. PMID: 7836452
- Exocytosis relating proteins in the nervous system. | Yamaguchi, K. and Akagawa, K. 1994. Neurosci Res. 20: 289-92. PMID: 7870381
- Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly. | Hayashi, T., et al. 1994. EMBO J. 13: 5051-61. PMID: 7957071
- A role for synaptotagmin (p65) in regulated exocytosis. | Elferink, LA., et al. 1993. Cell. 72: 153-9. PMID: 8422678
- Stimulation of NSF ATPase activity by alpha-SNAP is required for SNARE complex disassembly and exocytosis. | Barnard, RJ., et al. 1997. J Cell Biol. 139: 875-83. PMID: 9362506
- Structural organization of the synaptic exocytosis core complex. | Lin, RC. and Scheller, RH. 1997. Neuron. 19: 1087-94. PMID: 9390521
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SNAP 29 Antibody (E-5) | sc-390602 | 200 µg/ml | $316.00 | |||
SNAP 29 Antibody (E-5) AC | sc-390602 AC | 500 µg/ml, 25% agarose | $416.00 | |||
SNAP 29 Antibody (E-5) HRP | sc-390602 HRP | 200 µg/ml | $316.00 | |||
SNAP 29 Antibody (E-5) FITC | sc-390602 FITC | 200 µg/ml | $330.00 | |||
SNAP 29 Antibody (E-5) PE | sc-390602 PE | 200 µg/ml | $343.00 | |||
SNAP 29 Antibody (E-5) Alexa Fluor® 488 | sc-390602 AF488 | 200 µg/ml | $357.00 | |||
SNAP 29 Antibody (E-5) Alexa Fluor® 546 | sc-390602 AF546 | 200 µg/ml | $357.00 | |||
SNAP 29 Antibody (E-5) Alexa Fluor® 594 | sc-390602 AF594 | 200 µg/ml | $357.00 | |||
SNAP 29 Antibody (E-5) Alexa Fluor® 647 | sc-390602 AF647 | 200 µg/ml | $357.00 | |||
SNAP 29 Antibody (E-5) Alexa Fluor® 680 | sc-390602 AF680 | 200 µg/ml | $357.00 | |||
SNAP 29 Antibody (E-5) Alexa Fluor® 790 | sc-390602 AF790 | 200 µg/ml | $357.00 |