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SMTNL1 Antibody (B-7) is a mouse monoclonal IgG1 antibody that detects SMTNL1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SMTNL1, also known as smoothelin-like 1, is a 457 amino acid protein characterized by the presence of a calponin-homology (CH) domain, which is crucial for its role in smooth muscle contractility. SMTNL1 is predominantly expressed in contractile smooth muscle cells, where SMTNL1 localizes to the filament network and associates with actin stress fibers, playing a significant role in maintaining the structural integrity and functionality of these cells. Notably, SMTNL1 is part of the smoothelin family, which is essential for smooth muscle-specific functions, and proper functioning is vital for various physiological processes, including vascular tone regulation and gastrointestinal motility. The gene encoding SMTNL1 is located on human chromosome 11, a region associated with several genetic disorders, highlighting the importance of SMTNL1 in both health and disease. anti-SMTNL1 antibody (B-7) is an invaluable tool for researchers investigating smooth muscle biology and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SMTNL1 Antibody (B-7) | sc-390589 | 200 µg/ml | $322.00 | |||
SMTNL1 (B-7) Neutralizing Peptide | sc-390589 P | 100 µg/0.5 ml | $69.00 |