Smooth Muscle Actin Antibody (CGA7): sc-53015

Smooth Muscle Actin Antibody (CGA7) is a mouse monoclonal IgG2b kappa light chain antibody that detects Smooth Muscle Actin in mouse, rat, and human tissues through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-Smooth Muscle Actin antibody (CGA7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Actin plays a vital role in cellular structure and function as a key component of the cytoskeleton, providing mechanical support and shape to cells. Smooth Muscle Actin is predominantly located in the cytoplasm, where dynamic filaments form that are essential for various cellular processes, including motility, division, and intracellular transport. Smooth Muscle Actin′s ability to polymerize and depolymerize allows cells to adapt their shape and movement in response to external stimuli, which is particularly important in smooth muscle contraction and relaxation. Different isoforms of Actin, such as α-Actin in muscle tissues and β-Actin in non-muscle cells, highlight this protein′s versatility and specialization in various cellular contexts. Understanding Smooth Muscle Actin distribution and function is crucial for studying muscle physiology and pathologies, including vascular diseases and smooth muscle disorders.

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LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Smooth Muscle Actin Antibody (CGA7) has 130 citations in a variety of scientific publications.

Primary antibodies like Anti-Smooth Muscle Actin Antibody (CGA7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Smooth Muscle Actin Antibody (CGA7) Specifications

Alternate Product Name: Smooth Muscle Actin

Product Clone Name: CGA7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids:

Epitope Target: Actin

Epitope Species: chicken

Product Reactivity/Detection: α and γ Actin isotypes of smooth muscle cells

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: avian

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 130 citations in various scientific publications

Available Conjugates/Forms for Smooth Muscle Actin Antibody (CGA7): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Smooth Muscle Actin antibody is Smooth Muscle Actin Antibody (B4): sc-53142.