SLA Antibody (EP-2): sc-59364

SLA Antibody (EP-2) is a mouse monoclonal IgG2b antibody that detects SLA protein of human origin by immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-SLA antibody (EP-2) is available as a non-conjugated format, specifically designed to identify soluble liver antigens that are crucial for understanding liver-related diseases. SLA (EP-2) antibody plays a significant role in studying immune responses, particularly in autoimmune liver diseases, serving as a biomarker for conditions such as autoimmune hepatitis and primary biliary cholangitis. SLA autoantibodies show notably increased presence in patients infected with hepatitis C virus, highlighting importance in both diagnostic and therapeutic contexts. SLA protein primarily localizes in human hepatocytes, which are essential for various metabolic processes, including detoxification and protein synthesis. Understanding SLA protein localization provides insights into liver pathology and mechanisms underlying liver diseases. Using anti-SLA antibody (EP-2) in research can yield valuable information about liver function and immune system interaction with liver antigens, ultimately contributing to advancement of liver disease diagnostics and treatments.

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SLA Antibody (EP-2) References:

1. Soluble liver antigen: isolation of a 35-kd recombinant protein (SLA-p35) specifically recognizing sera from patients with autoimmune hepatitis.  |  Volkmann, M., et al. 2001. Hepatology. 33: 591-6. PMID: 11230739

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-SLA Antibody (EP-2) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-SLA Antibody (EP-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

SLA Antibody (EP-2) Specifications

Alternate Product Name: SLA

Product Clone Name: EP-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b

Amino Acids:

Epitope Target: SLA

Epitope Species: human

Product Reactivity/Detection: SLA in hepatocytes and the majority of hepatocarcinomas

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF, IHC(P)

Vialing Information: Each vial contains 100 µg IgG_2b in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for SLA Antibody (EP-2): N/A