SIRP-γ Antibody (OX118): sc-53113
- SIRP-γ Antibody (OX118) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against recombinant SIRP-γ of human origin
- recommended for detection of SIRP-γ and SIRP-α of human origin by FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SIRP-γ Antibody (OX118). These reagents are now offered in bundles with SIRP-γ Antibody (OX118) (see ordering information below).
SIRP-γ Antibody (OX118) is a mouse monoclonal IgG1 antibody that detects SIRP-γ in human samples through flow cytometry (FCM). SIRP-γ, also known as CD172g, is a transmembrane glycoprotein that plays a crucial role in immune regulation, particularly in the signaling pathways of T cells and B cells. SIRP-γ is predominantly expressed on the surface of T cells and a subset of B cells, where SIRP-γ interacts with CD47, a well-known "don′t eat me" signal that inhibits phagocytosis by macrophages. The interaction between SIRP-γ and CD47 is significant as SIRP-γ mediates unidirectional signaling, which is essential for maintaining immune homeostasis and preventing excessive immune responses. The structure of SIRP-γ, which includes an extracellular domain with immunoglobulin-like motifs, is vital for SIRP-γ function, as this structure allows for specific binding to ligands and subsequent downstream signaling. Using anti-SIRP-γ antibody (OX118) in research can provide insights into the regulatory mechanisms of immune cells and their interactions, which are critical for understanding various immunological conditions and potential therapeutic targets.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SIRP-γ Antibody (OX118) | sc-53113 | 200 µg/ml | $322.00 | |||
SIRP-γ Antibody (OX118): m-IgG Fc BP-HRP Bundle | sc-536891 | 200 µg Ab; 10 µg BP | $361.00 | |||
SIRP-γ Antibody (OX118): m-IgGκ BP-HRP Bundle | sc-534063 | 200 µg Ab; 40 µg BP | $361.00 | |||
SIRP-γ Antibody (OX118): m-IgG1 BP-HRP Bundle | sc-544881 | 200 µg Ab; 20 µg BP | $361.00 | |||
SIRP-γ Antibody (OX118) FITC | sc-53113 FITC | 200 µg/ml | $336.00 | |||
SIRP-γ Antibody (OX118) PE | sc-53113 PE | 200 µg/ml | $349.00 |