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SIRP-γ Antibody (OX116) - Flow Cytometry - Image 13812
SIRP-γ Antibody (OX116): sc-53111. Indirect FCM analysis of human peripheral blood leukocytes stained with SIRP-γ Antibody (OX116), followed by PE-conjugated goat anti-mouse IgG1: sc-3764. Black line histogram represents the isotype control, normal mouse IgG1: sc-3877.
SIRP-γ Antibody (OX116) - Flow Cytometry - Image 13812
SIRP-γ Antibody (OX116): sc-53111. Indirect FCM analysis of human peripheral blood leukocytes stained with SIRP-γ Antibody (OX116), followed by PE-conjugated goat anti-mouse IgG1: sc-3764. Black line histogram represents the isotype control, normal mouse IgG1: sc-3877.
SIRP-γ Antibody (OX116): sc-53111. Indirect FCM analysis of human peripheral blood leukocytes stained with SIRP-γ Antibody (OX116), followed by PE-conjugated goat anti-mouse IgG1: sc-3764. Black line histogram represents the isotype control, normal mouse IgG1: sc-3877.

SIRP-γ Antibody (OX116): sc-53111

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Datasheets
  • SIRP-γ Antibody (OX116) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against recombinant SIRP-γ of human origin
  • recommended for detection of SIRP-γ of human origin by FCM; may cross-react with SIRP-α
  • available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SIRP-γ Antibody (OX116). These reagents are now offered in bundles with SIRP-γ Antibody (OX116) (see ordering information below).
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    Additional SIRP Antibodies including SIRP-α, SIRP-β, SIRP-β 1 and SIRP-γ

    SIRP-γ Antibody (OX116) is a mouse monoclonal IgG1 antibody that detects SIRP-γ in human samples through flow cytometry (FCM). SIRP-γ, also known as CD172g, is a transmembrane glycoprotein that plays a crucial role in immune regulation, particularly in the signaling pathways of T cells and B cells. SIRP-γ is predominantly expressed on the surface of T cells and a subset of B cells, where SIRP-γ interacts with CD47, a well-known "don′t eat me" signal that inhibits phagocytosis by macrophages. The interaction between SIRP-γ and CD47 is significant as SIRP-γ mediates a unidirectional signaling cascade that helps maintain immune homeostasis and prevent excessive immune responses. Understanding SIRP-γ function is vital for developing therapeutic strategies aimed at modulating immune responses, particularly in cancer and autoimmune diseases. Anti-SIRP-γ antibody (OX116) is an essential tool for researchers investigating the complex interactions within the immune system and the potential for targeted therapies.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    SIRP-γ Antibody (OX116)

    sc-53111
    200 µg/ml
    		$322.00

    SIRP-γ Antibody (OX116): m-IgG Fc BP-HRP Bundle

    sc-536890
    200 µg Ab; 10 µg BP
    		$361.00

    SIRP-γ Antibody (OX116): m-IgGκ BP-HRP Bundle

    sc-534062
    200 µg Ab; 40 µg BP
    		$361.00

    SIRP-γ Antibody (OX116): m-IgG1 BP-HRP Bundle

    sc-544880
    200 µg Ab; 20 µg BP
    		$361.00

    SIRP-γ Antibody (OX116) FITC

    sc-53111 FITC
    200 µg/ml
    		$336.00

    SIRP-γ Antibody (OX116) PE

    sc-53111 PE
    200 µg/ml
    		$349.00

    How can SIRP-γ (OX116): sc-53111 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

    Asked by: Dr Ninau Qelp
    In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is available conjugated to phycoerythrin (sc-53111 PE) or fluoroscein (sc-53111 FITC).
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 3 out of 5 by from Good indirect FCM analysis of human peripheralGood indirect FCM analysis of human peripheral blood leukocytes stained with SIRP-g . -SCBT QC
    Date published: 2013-03-26
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    SIRP-γ Antibody (OX116) is rated 3.0 out of 5 by 1.
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