SIRP-β1 Antibody (LSB1.50): sc-53603
- SIRP-β1 Antibody (LSB1.50) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against SIRP-β1-D1D2-IgG of human origin
- recommended for detection of SIRP-β1 of human origin by WB, IP and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SIRP-β1 Antibody (LSB1.50). This work is in progress.
SIRP-β1 Antibody (LSB1.50) is a mouse monoclonal IgG1 antibody that detects SIRP-β1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). SIRP-β1 is a member of the signal-regulatory protein family, which plays a crucial role in modulating immune responses. Unlike its counterpart SIRP-α1, SIRP-β1 lacks a cytoplasmic domain, which means SIRP-β1 does not participate in the same signaling pathways, yet SIRP-β1 shares extensive sequence homology in its extracellular region. This unique structure allows SIRP-β1 to interact with various ligands, including CD47, which is vital for regulating immune cell signaling and maintaining self-tolerance. The interaction between SIRP-β1 and CD47 is particularly important as this interaction helps to prevent the phagocytosis of healthy cells by macrophages, thereby playing a protective role in the immune system. Anti-SIRP-β1 antibody (LSB1.50) is essential for researchers studying immune regulation and the mechanisms of cell signaling, providing valuable insights into potential therapeutic targets for autoimmune diseases and cancer.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SIRP-β1 Antibody (LSB1.50) | sc-53603 | 200 µg/ml | $322.00 | |||
SIRP-β1 Antibody (LSB1.50) FITC | sc-53603 FITC | 200 µg/ml | $336.00 | |||
SIRP-β1 Antibody (LSB1.50) PE | sc-53603 PE | 200 µg/ml | $349.00 |