Shh Antibody (G-5): sc-373779
- Shh Antibody (G-5) is a mouse monoclonal IgG1 κ, cited in 7 publications, provided at 200 µg/ml
- raised against amino acids 41-200 of Shh of human origin
- recommended for detection of a broad range of hedgehog family proteins of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and canine
- See Shh (E-1): sc-365112 for Shh antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Shh Antibody (G-5) for WB applications. These reagents are now offered in bundles with Shh Antibody (G-5) (see ordering information below).
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Shh Antibody (G-5) is a mouse monoclonal IgG1 antibody that detects Sonic hedgehog (Shh) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Shh antibody (G-5) plays a crucial role in studying Sonic hedgehog, which is essential for various developmental processes, including cell differentiation, tissue patterning, and organogenesis. Sonic hedgehog is secreted and functions as a signaling molecule that mediates cell-cell interactions during embryonic development. Proper functioning of Shh is vital, as disruptions in Shh signaling can lead to developmental disorders and contribute to the progression of certain cancers. Notably, Shh undergoes post-translational modifications, including glycosylation, which are important for stability, distribution, and interaction with receptors. These modifications enhance Shh′s ability to diffuse and interact with target cells, thereby influencing the signaling pathways that regulate cell fate decisions. Shh (G-5) antibody is an invaluable tool for researchers investigating the intricate roles of Sonic hedgehog in developmental biology and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Shh Antibody (G-5) | sc-373779 | 200 µg/ml | $322.00 | |||
Shh Antibody (G-5): m-IgG Fc BP-HRP Bundle | sc-540399 | 200 µg Ab; 10 µg BP | $361.00 | |||
Shh Antibody (G-5): m-IgG1 BP-HRP Bundle | sc-542095 | 200 µg Ab; 20 µg BP | $361.00 |