SH-PTP2 Antibody (D-1): sc-271106
- SH-PTP2 Antibody (D-1) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 373-404 within an internal region of SH-PTP2 of human origin
- recommended for detection of SH-PTP2 of mouse, rat, human and origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- See SH-PTP2 (B-1): sc-7384 for SH-PTP2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SH-PTP2 Antibody (D-1) for WB applications. These reagents are now offered in bundles with SH-PTP2 Antibody (D-1) (see ordering information below).
SH-PTP2 Antibody (D-1) is a mouse monoclonal IgG1 antibody that detects SH-PTP2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SH-PTP2, also known as PTP1D or Syp, plays a crucial role in cellular signaling by dephosphorylating tyrosine residues on proteins, thereby regulating various signaling pathways essential for cell growth, differentiation, and metabolism. SH-PTP2 is predominantly expressed in hematopoietic tissues, where SH-PTP2 is involved in the negative regulation of receptor tyrosine kinases, which are vital for proper immune responses. The presence of two SH2 domains in SH-PTP2 allows interaction with phosphotyrosine-containing proteins, facilitating the modulation of signaling cascades that influence cellular outcomes. Notably, SH-PTP2 shares strong sequence similarity with the Drosophila gene corkscrew, suggesting SH-PTP2 may serve as a human homolog, further emphasizing its importance in developmental processes and cellular communication. SH-PTP2 Antibody (D-1) is an invaluable tool for researchers exploring the intricate roles of this phosphatase in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SH-PTP2 Antibody (D-1) | sc-271106 | 200 µg/ml | $322.00 | |||
SH-PTP2 Antibody (D-1): m-IgG Fc BP-HRP Bundle | sc-537569 | 200 µg Ab; 10 µg BP | $361.00 | |||
SH-PTP2 Antibody (D-1): m-IgGκ BP-HRP Bundle | sc-534870 | 200 µg Ab; 40 µg BP | $361.00 | |||
SH-PTP2 Antibody (D-1): m-IgG1 BP-HRP Bundle | sc-545235 | 200 µg Ab; 20 µg BP | $361.00 | |||
SH-PTP2 (D-1) Neutralizing Peptide | sc-271106 P | 100 µg/0.5 ml | $69.00 |