SH-PTP1 Antibody (PTY15): sc-52890
- SH-PTP1 Antibody (PTY15) is a mouse monoclonal IgG1 κ provided at 100 µg/ml
- raised against full length SH-PTP1 of human origin
- recommended for detection of SH-PTP1 of mouse, rat and human origin by WB, IP, IF and ELISA
- See SH-PTP1 (D-11): sc-7289 for SH-PTP1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for SH-PTP1 Antibody (PTY15). This work is in progress.
SH-PTP1 Antibody (PTY15) is a mouse monoclonal IgG1 antibody that detects SH-PTP1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SH-PTP1, also known as PTP1C, HCP, and SHP, plays a crucial role in regulating protein tyrosyl phosphorylation within cells, a process vital for various cellular functions, including signal transduction and cell growth. SH-PTP1 is primarily expressed in hematopoietic cells and features two SH2 domains located N-terminal to the phosphatase domain. These SH2 domains mediate SH-PTP1′s interaction with specific phosphotyrosine-containing sites on autophosphorylated receptors, influencing initial receptor engagement with substrates. SH-PTP1′s ability to modulate signaling pathways highlights its importance in maintaining cellular homeostasis and potential implications in various diseases, including cancer and autoimmune disorders. Anti-SH-PTP1 antibody (PTY15) serves as an invaluable tool for researchers investigating tyrosine phosphorylation mechanisms and their impact on cellular behavior.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SH-PTP1 Antibody (PTY15) | sc-52890 | 100 µg/ml | $322.00 |