Date published: 2026-3-10

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Septin 1 Antibody (B-8): sc-398586

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Datasheets
  • Septin 1 Antibody (B-8) is a mouse monoclonal IgG2a κ Septin 1 antibody, cited in 2 publications, provided at 200 µg/ml
  • raised against amino acids 281-330 of Septin 1 of human origin
  • Septin 1 Antibody (B-8) is recommended for detection of Septin 1 of mouse, rat and human origin by WB, IP, IF and ELISA
  • Anti-Septin 1 Antibody (B-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Septin 1 Antibody (B-8) for WB applications. These reagents are now offered in bundles with Septin 1 Antibody (B-8) (see ordering information below).
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Septin 1 Antibody (B-8) is a mouse monoclonal IgG2a kappa light chain antibody that detects Septin 1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Septin 1 antibody (B-8) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Septin 1 plays a crucial role in regulating cytokinesis and forms heteropolymer complexes essential for cellular organization and growth. Septin 1 localization within the cytoskeleton maintains cell shape and facilitates cellular processes such as division and migration. Septin 1 interacts with other proteins, including Septin 2 and Septin 4, which are implicated in neurodegenerative diseases through association with tau-based paired helical filaments. Complex transcriptional regulation of septins generates alternatively spliced variants, highlighting Septin 1′s importance in cellular dynamics and potential role in various pathologies.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Septin 1 Antibody (B-8)

sc-398586
200 µg/ml
$322.00

Septin 1 Antibody (B-8): m-IgG Fc BP-HRP Bundle

sc-530856
200 µg Ab; 10 µg BP
$361.00

Septin 1 Antibody (B-8): m-IgGκ BP-HRP Bundle

sc-524405
200 µg Ab, 40 µg BP
$361.00

Septin 1 Antibody (B-8): m-IgG2a BP-HRP Bundle

sc-547612
200 µg Ab; 10 µg BP
$361.00

Septin 1 Antibody (B-8) AC

sc-398586 AC
500 µg/ml, 25% agarose
$424.00

Septin 1 Antibody (B-8) HRP

sc-398586 HRP
200 µg/ml
$322.00

Septin 1 Antibody (B-8) FITC

sc-398586 FITC
200 µg/ml
$336.00

Septin 1 Antibody (B-8) PE

sc-398586 PE
200 µg/ml
$349.00

Septin 1 Antibody (B-8) Alexa Fluor® 488

sc-398586 AF488
200 µg/ml
$364.00

Septin 1 Antibody (B-8) Alexa Fluor® 546

sc-398586 AF546
200 µg/ml
$364.00

Septin 1 Antibody (B-8) Alexa Fluor® 594

sc-398586 AF594
200 µg/ml
$364.00

Septin 1 Antibody (B-8) Alexa Fluor® 647

sc-398586 AF647
200 µg/ml
$364.00

Septin 1 Antibody (B-8) Alexa Fluor® 680

sc-398586 AF680
200 µg/ml
$364.00

Septin 1 Antibody (B-8) Alexa Fluor® 790

sc-398586 AF790
200 µg/ml
$364.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with Septin 1 (B-8): sc-398586 monoclonal antibody?

Asked by: Trav11
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-02-27
  • y_2026, m_3, d_9, h_9CST
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Rated 5 out of 5 by from Very good Western blot data of Septin 1 expressionVery good Western blot data of Septin 1 expression in Jurkat, HL-60 and Raji whole cell lysates. -SCBT QC
Date published: 2014-07-09
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Septin 1 Antibody (B-8) is rated 5.0 out of 5 by 1.
  • y_2026, m_3, d_9, h_9
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