SEA Antibody (A111): sc-73346

SEA Antibody (A111) is a mouse monoclonal IgG2a antibody that detects Staphylococcus enterotoxin A of Staphylococcus species by flow cytometry (FCM). Anti-Staphylococcus enterotoxin A antibody (A111) plays a crucial role in research related to foodborne illnesses caused by Staphylococcus aureus, as Staphylococcus enterotoxin A specifically acts as a potent superantigen responsible for severe gastrointestinal symptoms and systemic effects such as high fever and shock. The structure of Staphylococcus enterotoxin A consists of a single-chain polypeptide with a unique disulfide bond that stabilizes its conformation, allowing effective binding to class II major histocompatibility complex (MHC) molecules on antigen-presenting cells. This interaction triggers T cell activation, leading to the release of interleukin-2 and other cytokines, which can result in a robust immune response. Understanding the structural characteristics of Staphylococcus enterotoxin A (A111) not only aids in elucidating its mechanism of action but also provides insights into potential therapeutic interventions for managing food poisoning outbreaks. Staphylococcus enterotoxin A monoclonal antibody (A111) serves as an invaluable tool for researchers studying the pathogenicity of Staphylococcus aureus and the immune responses it elicits.

The preferred SEA antibody is SEA Antibody (A108): sc-73345.