Se46.8 Antibody (C-10): sc-377238
- Se46.8 Antibody (C-10) is a mouse monoclonal IgG2a κ Se46.8 antibody provided at 200 µg/ml
- raised against amino acids 1-86 representing full length Se46.8 of Streptococcus equi subsp. equi origin
- Se46.8 Antibody (C-10) is recommended for detection of Surface protein Se46.8 of Streptococcus equi subsp. equi 4047 and Streptococcus equi subsp. zooepidemicus MGCS10565 origin of and S. equi origin by WB, IP, IF and ELISA
- Anti-Se46.8 Antibody (C-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Se46.8 Antibody (C-10) for WB applications. These reagents are now offered in bundles with Se46.8 Antibody (C-10) (see ordering information below).
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Se46.8 Antibody (C-10) is a mouse monoclonal IgG2a kappa light chain antibody that detects Se46.8 protein of S. equi origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Se46.8 antibody (C-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. Se46.8 protein, also known as surface protein Se46.8, is an 86 amino acid protein that plays a crucial role in the pathogenesis of Streptococcus equi, a bacterium responsible for equine strangles. Surface protein Se46.8 is located on the bacterial cell, which is significant because this location facilitates interaction with host immune cells, thereby influencing immune response and overall virulence of the organism. Understanding Se46.8 protein function and location is essential for developing targeted therapies and vaccines against S. equi infections, making Se46.8 monoclonal antibody (C-10) a valuable tool for researchers studying this important pathogen.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Se46.8 Antibody (C-10) References:
- Getting to grips with strangles: an effective multi-component recombinant vaccine for the protection of horses from Streptococcus equi infection. | Guss, B., et al. 2009. PLoS Pathog. 5: e1000584. PMID: 19763180
- Molecular characterisation of 'strangles' outbreaks in the UK: the use of M-protein typing of Streptococcus equi ssp. equi. | Ivens, PA., et al. 2011. Equine Vet J. 43: 359-64. PMID: 21492215
- Association of Streptococcus equi with equine monocytes. | Mérant, C., et al. 2011. Vet Immunol Immunopathol. 143: 83-6. PMID: 21752476
- Streptococcus equi: a pathogen restricted to one host. | Waller, AS., et al. 2011. J Med Microbiol. 60: 1231-1240. PMID: 21757503
- Streptococcus equi subspecies equi infection (strangles) in horses. | Boyle, A. 2011. Compend Contin Educ Vet. 33: E1-7; quiz E8. PMID: 21870348
- Development of a novel mucosal vaccine against strangles by supercritical enhanced atomization spray-drying of Streptococcus equi extracts and evaluation in a mouse model. | Rodrigues, MA., et al. 2012. Eur J Pharm Biopharm. 82: 392-400. PMID: 22841882
- Detection of Streptococcus equi subspecies equi using a triplex qPCR assay. | Webb, K., et al. 2013. Vet J. 195: 300-4. PMID: 22884566
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Se46.8 Antibody (C-10) | sc-377238 | 200 µg/ml | $316.00 | |||
Se46.8 Antibody (C-10): m-IgG Fc BP-HRP Bundle | sc-529994 | 200 µg Ab; 10 µg BP | $354.00 | |||
Se46.8 Antibody (C-10): m-IgGκ BP-HRP Bundle | sc-523246 | 200 µg Ab, 40 µg BP | $354.00 | |||
Se46.8 Antibody (C-10): m-IgG2a BP-HRP Bundle | sc-547414 | 200 µg Ab; 10 µg BP | $354.00 | |||
Se46.8 Antibody (C-10) AC | sc-377238 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Se46.8 Antibody (C-10) HRP | sc-377238 HRP | 200 µg/ml | $316.00 | |||
Se46.8 Antibody (C-10) FITC | sc-377238 FITC | 200 µg/ml | $330.00 | |||
Se46.8 Antibody (C-10) PE | sc-377238 PE | 200 µg/ml | $343.00 | |||
Se46.8 Antibody (C-10) Alexa Fluor® 488 | sc-377238 AF488 | 200 µg/ml | $357.00 | |||
Se46.8 Antibody (C-10) Alexa Fluor® 546 | sc-377238 AF546 | 200 µg/ml | $357.00 | |||
Se46.8 Antibody (C-10) Alexa Fluor® 594 | sc-377238 AF594 | 200 µg/ml | $357.00 | |||
Se46.8 Antibody (C-10) Alexa Fluor® 647 | sc-377238 AF647 | 200 µg/ml | $357.00 | |||
Se46.8 Antibody (C-10) Alexa Fluor® 680 | sc-377238 AF680 | 200 µg/ml | $357.00 | |||
Se46.8 Antibody (C-10) Alexa Fluor® 790 | sc-377238 AF790 | 200 µg/ml | $357.00 |