SCD Antibody (D-5): sc-515875
- SCD Antibody (D-5) is a mouse monoclonal IgG1 λ SCD antibody, cited in 4 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 158-177 within an internal region of SCD1 of mouse origin
- SCD Antibody (D-5) is recommended for detection of SCD of human origin, SCD1, SCD2, SCD3 and SCD4 of mouse origin, and the corresponding rat homologs by WB, IP, IF and ELISA
- Anti-SCD Antibody (D-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for SCD Antibody (D-5) for WB applications. This reagent is now offered in a bundle with SCD Antibody (D-5) (see ordering information below).
SCD Antibody (D-5) is a mouse monoclonal IgG1 antibody that detects stearoyl-CoA desaturase (SCD) in human, mouse, rat, and other species by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-SCD antibody (D-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Stearoyl-CoA desaturase is a crucial microsomal enzyme involved in the synthesis of oleate and palmitoleate, which are essential monounsaturated fatty acids that contribute to the composition of membrane phospholipids, triglycerides, and cholesterol esters. SCD (D-5) antibody supports research in cellular lipid homeostasis, playing a significant role in the secretion of triacylglycerols and phospholipids, as well as in regulating cellular cholesterol levels. SCD undergoes rapid turnover within cells, making SCD an excellent model for studying the selective degradation of short-lived endoplasmic reticulum proteins. SCD expression increases in cells differentiating into adipocytes and in certain tumor cell lines, highlighting SCD′s importance in metabolic processes and potential implications in cancer biology. SCD gene family exhibits variability across species due to gene duplication events, and SCD expression is influenced by dietary levels of unsaturated fatty acids, further underscoring SCD′s relevance in both physiological and pathological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SCD Antibody (D-5) | sc-515875 | 200 µg/ml | $316.00 | |||
SCD Antibody (D-5): m-IgG Fc BP-HRP Bundle | sc-526441 | 200 µg Ab; 10 µg BP | $354.00 | |||
SCD Antibody (D-5) AC | sc-515875 AC | 500 µg/ml, 25% agarose | $416.00 | |||
SCD Antibody (D-5) HRP | sc-515875 HRP | 200 µg/ml | $316.00 | |||
SCD Antibody (D-5) FITC | sc-515875 FITC | 200 µg/ml | $330.00 | |||
SCD Antibody (D-5) PE | sc-515875 PE | 200 µg/ml | $343.00 | |||
SCD Antibody (D-5) Alexa Fluor® 488 | sc-515875 AF488 | 200 µg/ml | $357.00 | |||
SCD Antibody (D-5) Alexa Fluor® 546 | sc-515875 AF546 | 200 µg/ml | $357.00 | |||
SCD Antibody (D-5) Alexa Fluor® 594 | sc-515875 AF594 | 200 µg/ml | $357.00 | |||
SCD Antibody (D-5) Alexa Fluor® 647 | sc-515875 AF647 | 200 µg/ml | $357.00 | |||
SCD Antibody (D-5) Alexa Fluor® 680 | sc-515875 AF680 | 200 µg/ml | $357.00 | |||
SCD Antibody (D-5) Alexa Fluor® 790 | sc-515875 AF790 | 200 µg/ml | $357.00 |