SCAMP1 Antibody (G-8): sc-393236

SCAMP1 Antibody (G-8) is a mouse monoclonal IgG1 antibody that detects secretory carrier membrane protein 1 (SCAMP1) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SCAMP1 plays a crucial role in membrane trafficking and vesicle recycling, which are essential processes for maintaining cellular homeostasis and facilitating communication between cells. SCAMP1 is primarily located in the post-Golgi membranes and is involved in endocytosis, where SCAMP1 aids in the budding of transport vesicles from the plasma membrane and the Golgi complex. The structural integrity of SCAMP1, characterized by multiple N-terminal NPF repeats and four highly conserved transmembrane regions, is vital for interaction with EH domain proteins, which are key players in the vesicle budding process. Notably, SCAMP1 is subject to regulation through tyrosine phosphorylation by the epidermal growth factor receptor, highlighting SCAMP1′s dynamic role in cellular signaling pathways. While SCAMP1 is expressed across various tissues, SCAMP1 is particularly abundant in neural tissue, where SCAMP1 is found in high concentrations within synaptic vesicles, underscoring SCAMP1′s importance in neurotransmitter release and synaptic function. Anti-SCAMP1 antibody (G-8) is an invaluable tool for researchers studying the intricate mechanisms of membrane dynamics and cellular communication.

The preferred SCAMP1 antibody is SCAMP1 Antibody (D-1): sc-398154.