Anti-SAF-B2 Antibody (C-5) is a mouse monoclonal IgG2b (kappa light chain) SAF-B2 antibody provided at 200 µg/ml
specific for an epitope mapping between amino acids 898-922 near the C-terminus of SAF-B2 of human origin
Anti-SAF-B2 Antibody (C-5) is recommended for detection of SAF-B2 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-SAF-B2 Antibody (C-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of SAF-B2 (C-5): sc-514963.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for SAF-B2 Antibody (C-5) for WB applications. This reagent is now offered in a bundle with SAF-B2 Antibody (C-5) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
SAF-B2 Antibody (C-5) is a high quality monoclonal SAF-B2 antibody (also designated SAF-B2 antibody) suitable for the detection of the SAF-B2 protein of mouse, rat and human origin. SAF-B2 Antibody (C-5) is available as both the non-conjugated anti-SAF-B2 antibody form, as well as multiple conjugated forms of anti-SAF-B2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to pre-mRNA processing and transport. hnRNPs also bind heterogeneous nuclear RNA (hnRNA), the transcripts produced by RNA polymerase II. SAF-B2 (scaffold attachment factor B2) is a nuclear matrix-associated protein that binds to matrix- or scaffold-associating regions (MARs or SARs) on DNA and interacts with RNA polymerase II and serine-/arginine-rich RNA processing factors (SR proteins). SAF-B2, and the related SAF-B, bind to the estrogen receptor (ER) and are expressed in several breast cancer cell lines at varying levels. Subsequently, SAF-B and SAF-B2 may play a role in breast cancer by mediating cellular proliferation and division. Unlike SAF-B, which is exclusively nuclear, SAF-B2 is found in the cytoplasm as well as the nucleus.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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