Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The cohesion complex is a multi-protein structure that is required for cohesion of sister chromatids after DNA replication and may be involved in mitotic spindle pole assembly. There are several versions of the cohesion complex, all of which are composed of a heterodimer between SMC1 (SMC1A or SMC1B) and SMC3, as well as a linker protein called Rad21 and an additional binding protein. Depending on the complex, the additional protein can be SA-1 (stromal antigen 1), SA-2 (stromal antigen 2) or SA-3 (stromal antigen 3). SA-2, also known as STAG2, is a 1,231 amino acid component of the cohesion complex that interacts directly with Rad21. Localized to the nucleus, SA-2 associates with chromatin and, upon phosphorylation by Plk, dissociates from chromatin to allow proper chromosome separation during anaphase. SA-2 is able to enhance the activity of tumor necrosis factor alpha (TNFα) and may be a putative transcriptional regulator.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.