S-100 β chain Antibody (G-9): sc-398707

S-100 β chain Antibody (G-9) is a mouse monoclonal IgG1 antibody that detects S-100 β chain in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). S-100 β chain is a member of the S-100 protein family, which plays a crucial role in various cellular processes, including the regulation of cell cycle progression and differentiation. S-100 β chain (G-9) antibody helps identify this protein′s involvement in calcium signaling pathways, where S-100 β chain can activate calcium-induced calcium release, thereby influencing cellular responses to calcium fluctuations. S-100 β chain is primarily localized in the cytoplasm and nuclei of astrocytes, Schwann cells, and certain tumors, such as ependymomas and astrogliomas, highlighting its significance in both normal and pathological states of the nervous system. The presence of S-100 β chain in benign and malignant melanocytic tumors, as well as in Langerhans cells in the skin, further underscores its potential as a biomarker in cancer research. Anti-S-100 β chain antibody (G-9) is an essential tool for researchers investigating the roles of S-100 proteins in health and disease, providing insights into their functions and interactions within various biological contexts.

The preferred S-100 α/β chain antibody is S-100 α/β chain Antibody (B32.1): sc-58839.