RWDD4A Antibody (C-3): sc-377462
- RWDD4A Antibody (C-3) is a mouse monoclonal IgG2a κ RWDD4A antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 151-183 near the C-terminus of RWDD4A of human origin
- RWDD4A Antibody (C-3) is recommended for detection of RWDD4A of mouse, rat, human and avian origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- Anti-RWDD4A Antibody (C-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for RWDD4A Antibody (C-3) for WB and IHC(P) applications. These reagents are now offered in bundles with RWDD4A Antibody (C-3) (see ordering information below).
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RWDD4A Antibody (C-3) is a mouse monoclonal IgG2a kappa light chain antibody that detects RWDD4A protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-RWDD4A antibody (C-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. RWDD4A, also known as RWD domain-containing protein 4, consists of 188 amino acids and features a single RWD domain, which is crucial for protein-protein interactions and plays a significant role in various cellular processes, including stress response and protein degradation pathways. The presence of the RWD domain facilitates RWDD4A binding to other proteins, potentially influencing their stability and function, thereby impacting cellular homeostasis. RWDD4 gene is highly conserved across multiple species, including chimpanzees, cows, mice, rats, chickens, zebrafish, fruit flies, and mosquitoes, and is located on human chromosome 4q35.1, a region that harbors nearly 900 genes and is associated with several genetic disorders. Understanding RWDD4A function and interactions is essential for elucidating its role in health and disease, particularly in conditions linked to chromosome 4 abnormalities.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
RWDD4A Antibody (C-3) References:
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. | Hillier, LW., et al. 2005. Nature. 434: 724-31. PMID: 15815621
- Selective neuronal degeneration in Huntington's disease. | Cowan, CM. and Raymond, LA. 2006. Curr Top Dev Biol. 75: 25-71. PMID: 16984809
- Syndromic craniosynostosis: from history to hydrogen bonds. | Cunningham, ML., et al. 2007. Orthod Craniofac Res. 10: 67-81. PMID: 17552943
- Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. | Ruiz-Perez, VL., et al. 2007. Development. 134: 2903-12. PMID: 17660199
- Growth hormone analysis and treatment in Ellis-van Creveld syndrome. | Versteegh, FG., et al. 2007. Am J Med Genet A. 143A: 2113-21. PMID: 17702014
- Metabolic phenotype of methylmalonic acidemia in mice and humans: the role of skeletal muscle. | Chandler, RJ., et al. 2007. BMC Med Genet. 8: 64. PMID: 17937813
- Muenke syndrome (FGFR3-related craniosynostosis): expansion of the phenotype and review of the literature. | Doherty, ES., et al. 2007. Am J Med Genet A. 143A: 3204-15. PMID: 18000976
- Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice. | Stack, EC., et al. 2007. J Neurosci. 27: 12908-15. PMID: 18032664
- Snail1 is a transcriptional effector of FGFR3 signaling during chondrogenesis and achondroplasias. | de Frutos, CA., et al. 2007. Dev Cell. 13: 872-83. PMID: 18061568
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RWDD4A Antibody (C-3) | sc-377462 | 200 µg/ml | $322.00 | |||
RWDD4A Antibody (C-3): m-IgGκ BP-HRP Bundle | sc-523336 | 200 µg Ab, 40 µg BP | $361.00 | |||
RWDD4A Antibody (C-3): m-IgG2a BP-HRP Bundle | sc-546155 | 200 µg Ab; 10 µg BP | $361.00 | |||
RWDD4A Antibody (C-3) AC | sc-377462 AC | 500 µg/ml, 25% agarose | $424.00 | |||
RWDD4A Antibody (C-3) HRP | sc-377462 HRP | 200 µg/ml | $322.00 | |||
RWDD4A Antibody (C-3) FITC | sc-377462 FITC | 200 µg/ml | $336.00 | |||
RWDD4A Antibody (C-3) PE | sc-377462 PE | 200 µg/ml | $349.00 | |||
RWDD4A Antibody (C-3) Alexa Fluor® 488 | sc-377462 AF488 | 200 µg/ml | $364.00 | |||
RWDD4A Antibody (C-3) Alexa Fluor® 546 | sc-377462 AF546 | 200 µg/ml | $364.00 | |||
RWDD4A Antibody (C-3) Alexa Fluor® 594 | sc-377462 AF594 | 200 µg/ml | $364.00 | |||
RWDD4A Antibody (C-3) Alexa Fluor® 647 | sc-377462 AF647 | 200 µg/ml | $364.00 | |||
RWDD4A Antibody (C-3) Alexa Fluor® 680 | sc-377462 AF680 | 200 µg/ml | $364.00 | |||
RWDD4A Antibody (C-3) Alexa Fluor® 790 | sc-377462 AF790 | 200 µg/ml | $364.00 | |||
RWDD4A (C-3) Neutralizing Peptide | sc-377462 P | 100 µg/0.5 ml | $69.00 |