RWDD1 Antibody (C-8): sc-514496
- RWDD1 Antibody (C-8) is a mouse monoclonal IgG1 κ RWDD1 antibody provided at 200 µg/ml
- raised against amino acids 55-122 mapping within an internal region of RWDD1 of human origin
- RWDD1 Antibody (C-8) is recommended for detection of RWDD1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-RWDD1 Antibody (C-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for RWDD1 Antibody (C-8) for WB applications. These reagents are now offered in bundles with RWDD1 Antibody (C-8) (see ordering information below).
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RWDD1 Antibody (C-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects RWDD1 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RWDD1 (C-8) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. RWDD1, also known as CGI-24 or PTD013, consists of 243 amino acids and belongs to the RWDD1/GIR2 family, characterized by its RWD domain at the N-terminal region. RWDD1 plays a crucial role in cellular processes by interacting with DRG2 (developmentally regulated GTP binding protein 2), which is essential for cell proliferation, differentiation, and apoptosis. The protective interaction between RWDD1 and DRG2 prevents DRG2 from undergoing proteolytic degradation, maintaining functional levels within the cytoplasm. RWDD1 is encoded on human chromosome 6, a region comprising nearly 6% of the human genome and associated with various health conditions, including early onset intestinal cancer and other genetic disorders. Understanding RWDD1 and its interactions is vital for uncovering the underlying mechanisms of these diseases and may provide insights into potential therapeutic targets.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
RWDD1 Antibody (C-8) References:
- The DNA sequence and analysis of human chromosome 6. | Mungall, AJ., et al. 2003. Nature. 425: 805-11. PMID: 14574404
- A stop codon mutation in COL11A2 induces exon skipping and leads to non-ocular Stickler syndrome. | Vuoristo, MM., et al. 2004. Am J Med Genet A. 130A: 160-4. PMID: 15372529
- Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. | McQueen, MB., et al. 2005. Am J Hum Genet. 77: 582-95. PMID: 16175504
- A disease state mutation unfolds the parkin ubiquitin-like domain. | Safadi, SS. and Shaw, GS. 2007. Biochemistry. 46: 14162-9. PMID: 18004887
- Identification and characterization of a novel thymus aging related protein Rwdd1. | Kang, N., et al. 2008. Cell Mol Immunol. 5: 279-85. PMID: 18761815
- Rwdd1, a thymus aging related molecule, is a new member of the intrinsically unstructured protein family. | Kang, N., et al. 2008. Cell Mol Immunol. 5: 333-9. PMID: 18954556
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. | Nagase, T., et al. 1997. DNA Res. 4: 141-50. PMID: 9205841
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RWDD1 Antibody (C-8) | sc-514496 | 200 µg/ml | $322.00 | |||
RWDD1 Antibody (C-8): m-IgG Fc BP-HRP Bundle | sc-531146 | 200 µg Ab; 10 µg BP | $361.00 | |||
RWDD1 Antibody (C-8): m-IgGκ BP-HRP Bundle | sc-524746 | 200 µg Ab, 40 µg BP | $361.00 | |||
RWDD1 Antibody (C-8): m-IgG1 BP-HRP Bundle | sc-544416 | 200 µg Ab; 20 µg BP | $361.00 | |||
RWDD1 Antibody (C-8) AC | sc-514496 AC | 500 µg/ml, 25% agarose | $424.00 | |||
RWDD1 Antibody (C-8) HRP | sc-514496 HRP | 200 µg/ml | $322.00 | |||
RWDD1 Antibody (C-8) FITC | sc-514496 FITC | 200 µg/ml | $336.00 | |||
RWDD1 Antibody (C-8) PE | sc-514496 PE | 200 µg/ml | $349.00 | |||
RWDD1 Antibody (C-8) Alexa Fluor® 488 | sc-514496 AF488 | 200 µg/ml | $364.00 | |||
RWDD1 Antibody (C-8) Alexa Fluor® 546 | sc-514496 AF546 | 200 µg/ml | $364.00 | |||
RWDD1 Antibody (C-8) Alexa Fluor® 594 | sc-514496 AF594 | 200 µg/ml | $364.00 | |||
RWDD1 Antibody (C-8) Alexa Fluor® 647 | sc-514496 AF647 | 200 µg/ml | $364.00 | |||
RWDD1 Antibody (C-8) Alexa Fluor® 680 | sc-514496 AF680 | 200 µg/ml | $364.00 | |||
RWDD1 Antibody (C-8) Alexa Fluor® 790 | sc-514496 AF790 | 200 µg/ml | $364.00 |