RSL1D1 Antibody (E-12): sc-376302
- RSL1D1 Antibody (E-12) is a mouse monoclonal IgG2b κ RSL1D1 antibody provided at 200 µg/ml
- raised against amino acids 1-240 mapping at the N-terminus of RSL1D1 of mouse origin
- RSL1D1 Antibody (E-12) is recommended for detection of RSL1D1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-RSL1D1 Antibody (E-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for RSL1D1 Antibody (E-12) for WB applications. This reagent is now offered in a bundle with RSL1D1 Antibody (E-12) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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RSL1D1 Antibody (E-12) is a mouse monoclonal IgG2b kappa light chain antibody that detects RSL1D1 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RSL1D1 (E-12) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. RSL1D1, also known as CATX-11, PBK1, L12, or CSIG, is a 490 amino acid nuclear protein that belongs to the ribosomal protein L1P family and plays a crucial role in ribosome biogenesis and cellular stress responses. RSL1D1 expression in the placenta highlights its importance in developmental processes, while the presence of numerous phosphorylated amino acid residues suggests that post-translational modifications may regulate RSL1D1 function and interactions with other proteins. RSL1D1 is encoded by a gene located on human chromosome 16p13.13, a region associated with various genetic disorders, including giant axonal neuropathy and Rubinstein-Taybi syndrome, which underscores RSL1D1 significance in both normal physiology and disease states. RSL1D1 ability to interact with specific proteins involved in cellular signaling pathways further emphasizes RSL1D1 potential as a biomarker and therapeutic target in research and clinical applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
RSL1D1 Antibody (E-12) References:
- The gene encoding gigaxonin, a new member of the cytoskeletal BTB/kelch repeat family, is mutated in giant axonal neuropathy. | Bomont, P., et al. 2000. Nat Genet. 26: 370-4. PMID: 11062483
- Giant axonal neuropathy (GAN): case report and two novel mutations in the gigaxonin gene. | Kuhlenbäumer, G., et al. 2002. Neurology. 58: 1273-6. PMID: 11971098
- Genetics of inflammatory bowel disease: progress and prospects. | Mathew, CG. and Lewis, CM. 2004. Hum Mol Genet. 13 Spec No 1: R161-8. PMID: 14764625
- Advances in the genetics of inflammatory bowel disease. | Cho, JH. 2004. Curr Gastroenterol Rep. 6: 467-73. PMID: 15527676
- The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor. | Crawford, NP., et al. 2009. J Biol Chem. 284: 28660-73. PMID: 19710015
- The Rubinstein-Taybi syndrome: occurrence in two sets of identical twins. | Baraitser, M. and Preece, MA. 1983. Clin Genet. 23: 318-20. PMID: 6682729
- Rubinstein-Taybi syndrome caused by submicroscopic deletions within 16p13.3. | Breuning, MH., et al. 1993. Am J Hum Genet. 52: 249-54. PMID: 8430691
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RSL1D1 Antibody (E-12) | sc-376302 | 200 µg/ml | $322.00 | |||
RSL1D1 Antibody (E-12): m-IgGκ BP-HRP Bundle | sc-522910 | 200 µg Ab, 40 µg BP | $361.00 | |||
RSL1D1 Antibody (E-12) AC | sc-376302 AC | 500 µg/ml, 25% agarose | $424.00 | |||
RSL1D1 Antibody (E-12) HRP | sc-376302 HRP | 200 µg/ml | $322.00 | |||
RSL1D1 Antibody (E-12) FITC | sc-376302 FITC | 200 µg/ml | $336.00 | |||
RSL1D1 Antibody (E-12) PE | sc-376302 PE | 200 µg/ml | $349.00 | |||
RSL1D1 Antibody (E-12) Alexa Fluor® 488 | sc-376302 AF488 | 200 µg/ml | $364.00 | |||
RSL1D1 Antibody (E-12) Alexa Fluor® 546 | sc-376302 AF546 | 200 µg/ml | $364.00 | |||
RSL1D1 Antibody (E-12) Alexa Fluor® 594 | sc-376302 AF594 | 200 µg/ml | $364.00 | |||
RSL1D1 Antibody (E-12) Alexa Fluor® 647 | sc-376302 AF647 | 200 µg/ml | $364.00 | |||
RSL1D1 Antibody (E-12) Alexa Fluor® 680 | sc-376302 AF680 | 200 µg/ml | $364.00 | |||
RSL1D1 Antibody (E-12) Alexa Fluor® 790 | sc-376302 AF790 | 200 µg/ml | $364.00 |