RNMTL1 Antibody (A-5): sc-398973
- RNMTL1 Antibody (A-5) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 269-287 within an internal region of RNMTL1 of human origin
- recommended for detection of RNMTL1 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for RNMTL1 Antibody (A-5) for WB applications. These reagents are now offered in bundles with RNMTL1 Antibody (A-5) (see ordering information below).
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RNMTL1 Antibody (A-5) is a mouse monoclonal IgG1 antibody that detects RNMTL1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RNMTL1, also known as HC90, is a 420 amino acid protein that belongs to the RNA methyltransferase trmH family, playing a crucial role in the modification of RNA molecules. RNMTL1 modification is essential for various cellular processes, including cell growth and signaling pathways, and has been implicated in tumor development and progression. RNMTL1 is expressed in normal liver tissue as well as in hepatocarcinoma, highlighting RNMTL1′s potential involvement in cancer biology. The gene encoding RNMTL1 is located on human chromosome 17, a region that is significant due to its association with key tumor suppressor genes such as p53 and BRCA1. p53 protein is vital for maintaining cellular genetic integrity, as p53 regulates cell fate decisions between DNA repair and apoptosis, while BRCA1 is recognized for its role in DNA repair and its association with hereditary breast and ovarian cancers. RNMTL1′s interaction with these critical pathways underscores RNMTL1′s importance in both normal cellular function and cancer pathology, making anti-RNMTL1 antibody (A-5) a valuable tool for researchers studying RNA modifications and their implications in disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RNMTL1 Antibody (A-5) | sc-398973 | 200 µg/ml | $322.00 | |||
RNMTL1 Antibody (A-5): m-IgG Fc BP-HRP Bundle | sc-538554 | 200 µg Ab; 10 µg BP | $361.00 | |||
RNMTL1 Antibody (A-5): m-IgGκ BP-HRP Bundle | sc-536191 | 200 µg Ab; 40 µg BP | $361.00 | |||
RNMTL1 Antibody (A-5): m-IgG1 BP-HRP Bundle | sc-545763 | 200 µg Ab; 20 µg BP | $361.00 | |||
RNMTL1 (A-5) Neutralizing Peptide | sc-398973 P | 100 µg/0.5 ml | $69.00 |