Ribosomal Protein S21 Antibody (G-11): sc-514411

Ribosomal Protein S21 Antibody (G-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects Ribosomal Protein S21 (RPS21) of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-RPS21 antibody (G-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. RPS21, also known as 40S ribosomal protein S21 or 8.2 kDa differentiation factor, is a crucial component of the ribosomal machinery, specifically part of the 40S ribosomal subunit, which plays a vital role in protein synthesis initiation. This 83 amino acid protein functions in the cytoplasm, contributing to ribosome assembly and function, ensuring accurate translation of messenger RNA into proteins. RPS21 supports essential cellular growth and metabolism through proper ribosome function. RPS21 is encoded by multigene families that include processed pseudogenes, highlighting evolutionary significance and complex regulation. Understanding RPS21′s role in ribosome assembly and function provides insights into protein synthesis mechanisms and their implications in health and disease.

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Ribosomal Protein S21 Antibody (G-11) References:

1. [Cloning and characterization of the human ribosomal protein S21 gene [].  |  Smirnova, EV., et al. 2000. Bioorg Khim. 26: 392-6. PMID: 10900511
2. The human ribosomal protein genes: sequencing and comparative analysis of 73 genes.  |  Yoshihama, M., et al. 2002. Genome Res. 12: 379-90. PMID: 11875025
3. Interactions of ACTH and norepinephrine on the activity of rat hippocampal cells.  |  Segal, M. 1976. Neuropharmacology. 15: 329-33. PMID: 180450
4. Diversity of acid stress resistant variants of Listeria monocytogenes and the potential role of ribosomal protein S21 encoded by rpsU.  |  Metselaar, KI., et al. 2015. Front Microbiol. 6: 422. PMID: 26005439
5. Mutations driving CLL and their evolution in progression and relapse.  |  Landau, DA., et al. 2015. Nature. 526: 525-30. PMID: 26466571
6. Down-Regulation of Ribosomal Protein RPS21 Inhibits Invasive Behavior of Osteosarcoma Cells Through the Inactivation of MAPK Pathway.  |  Wang, T., et al. 2020. Cancer Manag Res. 12: 4949-4955. PMID: 32612383
7. Phage-encoded ribosomal protein S21 expression is linked to late-stage phage replication.  |  Chen, LX., et al. 2022. ISME Commun. 2: 31. PMID: 37938675
8. Ribosomal protein S21 is required for full activity in the initiation of protein synthesis.  |  Held, WA., et al. 1974. Mol Gen Genet. 128: 11-22. PMID: 4595779
9. The function of ribosomal protein S21 in protein synthesis.  |  Van Duin, J. and Wijnands, R. 1981. Eur J Biochem. 118: 615-9. PMID: 7028483
10. A new human leukemia cell 8.2 kDa differentiation factor: isolation and primary structure.  |  Kostanyan, IA., et al. 1994. FEBS Lett. 356: 327-9. PMID: 7805865
11. Primary structure of human ribosomal protein S21.  |  Bhat, KS. and Morrison, SG. 1993. Nucleic Acids Res. 21: 2939. PMID: 8332502
12. A map of 75 human ribosomal protein genes.  |  Kenmochi, N., et al. 1998. Genome Res. 8: 509-23. PMID: 9582194

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Ribosomal Protein S21 Antibody (G-11) has 2 citations in a variety of scientific publications.

Primary antibodies like Anti-Ribosomal Protein S21 Antibody (G-11) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Ribosomal Protein S21 Antibody (G-11) Specifications

Alternate Product Name: Ribosomal Protein S21

Product Clone Name: G-11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-76

Epitope Target: Ribosomal Protein S21

Epitope Species: human

Product Reactivity/Detection: Ribosomal Protein S21

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 2 citations in various scientific publications

Available Conjugates/Forms for Ribosomal Protein S21 Antibody (G-11): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin