Rho GDI Antibody (E-1): sc-373883
- Rho GDI Antibody (E-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 1-100 mapping at the N-terminus of Rho GDIα of human origin
- recommended for detection of Rho GDIα, Ly-GDI (Rho GDIβ) and Rho GDIγ of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Rho GDI Antibody (E-1) for WB applications. These reagents are now offered in bundles with Rho GDI Antibody (E-1) (see ordering information below).
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Rho GDI Antibody (E-1) is a mouse monoclonal IgG1 antibody that detects Rho GDI in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Rho GDI antibody (E-1) plays a crucial role in studying the regulation of Rho GTPases, which are pivotal in various cellular processes, including cell migration, adhesion, and cytoskeletal dynamics. Rho GDI proteins, including Rho GDIα, Ly-GDI, and Rho GDIγ, interact with several Ras-like GTP-binding proteins, such as Rho A, Rho B, Rac, and Cdc42, thereby influencing their activity and localization. Notably, Rho GDI interaction with these GTPases is essential for maintaining their inactive GDP-bound state, which prevents inappropriate activation of signaling pathways that could lead to uncontrolled cell proliferation or migration. Specific expression of Ly-GDI in hematopoietic cells, particularly in B and T lymphocyte cell lines, highlights its importance in immune responses and suggests Rho GDI (E-1) antibody could be a valuable tool for studying immune cell signaling and function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rho GDI Antibody (E-1) | sc-373883 | 200 µg/ml | $322.00 | |||
Rho GDI Antibody (E-1): m-IgG Fc BP-HRP Bundle | sc-537879 | 200 µg Ab; 10 µg BP | $361.00 | |||
Rho GDI Antibody (E-1): m-IgGκ BP-HRP Bundle | sc-535326 | 200 µg Ab; 40 µg BP | $361.00 | |||
Rho GDI Antibody (E-1): m-IgG1 BP-HRP Bundle | sc-545424 | 200 µg Ab; 20 µg BP | $361.00 |