Rho G Antibody (1F3 B3 E5): sc-80015
- Rho G Antibody (1F3 B3 E5) is a mouse monoclonal IgG2a κ Rho G antibody, cited in 11 publications, provided at 200 µg/ml
- raised against a C-terminal Rho G peptide of mouse origin
- Rho G Antibody (1F3 B3 E5) is recommended for detection of endogenous Rho G of mouse, rat and human origin by WB and IP
- Anti-Rho G Antibody (1F3 B3 E5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Rho G Antibody (1F3 B3 E5) for WB applications. This reagent is now offered in a bundle with Rho G Antibody (1F3 B3 E5) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Rho G Antibody (1F3 B3 E5) is a mouse monoclonal IgG2a kappa light chain antibody that detects Rho G protein of mouse, rat, and human origin by western blotting (WB) and immunoprecipitation (IP). anti-Rho G antibody (1F3 B3 E5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Rho G protein plays a crucial role in regulating the actin cytoskeleton, which is essential for various cellular processes such as cell migration, adhesion, and division. Proper function of Rho G is vital for maintaining cellular architecture and facilitating communication between cells, making Rho G a key player in developmental processes and tissue homeostasis. Dysregulation of Rho G has been implicated in several pathological conditions, including cancer metastasis and cardiovascular diseases, highlighting the importance of studying Rho G in both basic and applied research. Rho G protein, like other members of the Ras superfamily, contains a carboxy-terminal CAAX motif that is critical for post-translational modification and membrane localization, further emphasizing the significance of Rho G in cellular signaling pathways.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Rho G Antibody (1F3 B3 E5) References:
- Post-translational modifications of p21rho proteins. | Adamson, P., et al. 1992. J Biol Chem. 267: 20033-8. PMID: 1400319
- RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration. | van Buul, JD., et al. 2007. J Cell Biol. 178: 1279-93. PMID: 17875742
- Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism. | Hiramoto-Yamaki, N., et al. 2010. J Cell Biol. 190: 461-77. PMID: 20679435
- Expression of the ras-related ralA, rho12 and rab genes in adult mouse tissues. | Olofsson, B., et al. 1988. Oncogene. 3: 231-4. PMID: 2457862
- Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins. | Garrett, MD., et al. 1989. J Biol Chem. 264: 10-3. PMID: 2491843
- Scrape-loading of Swiss 3T3 cells with ras protein rapidly activates protein kinase C in the absence of phosphoinositide hydrolysis. | Morris, JD., et al. 1989. Oncogene. 4: 27-31. PMID: 2536916
- Tyrosine Phosphorylation of SGEF Regulates RhoG Activity and Cell Migration. | Okuyama, Y., et al. 2016. PLoS One. 11: e0159617. PMID: 27437949
- Involvement of Tiam1, RhoG and ELMO2/ILK in Rac1-mediated phagocytosis in human trabecular meshwork cells. | Peotter, JL., et al. 2016. Exp Cell Res. 347: 301-11. PMID: 27539661
- The ras superfamily proteins. | Chardin, P. 1988. Biochimie. 70: 865-8. PMID: 3145021
- ras genes. | Barbacid, M. 1987. Annu Rev Biochem. 56: 779-827. PMID: 3304147
- Nucleotide sequence of human rho cDNA clone 12. | Yeramian, P., et al. 1987. Nucleic Acids Res. 15: 1869. PMID: 3822842
- A novel ras-related gene family. | Madaule, P. and Axel, R. 1985. Cell. 41: 31-40. PMID: 3888408
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rho G Antibody (1F3 B3 E5) | sc-80015 | 200 µg/ml | $322.00 | |||
Rho G Antibody (1F3 B3 E5): m-IgGκ BP-HRP Bundle | sc-521155 | 200 µg Ab, 40 µg BP | $361.00 | |||
Rho G Antibody (1F3 B3 E5) AC | sc-80015 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Rho G Antibody (1F3 B3 E5) HRP | sc-80015 HRP | 200 µg/ml | $322.00 | |||
Rho G Antibody (1F3 B3 E5) FITC | sc-80015 FITC | 200 µg/ml | $336.00 | |||
Rho G Antibody (1F3 B3 E5) PE | sc-80015 PE | 200 µg/ml | $349.00 | |||
Rho G Antibody (1F3 B3 E5) Alexa Fluor® 488 | sc-80015 AF488 | 200 µg/ml | $364.00 | |||
Rho G Antibody (1F3 B3 E5) Alexa Fluor® 546 | sc-80015 AF546 | 200 µg/ml | $364.00 | |||
Rho G Antibody (1F3 B3 E5) Alexa Fluor® 594 | sc-80015 AF594 | 200 µg/ml | $364.00 | |||
Rho G Antibody (1F3 B3 E5) Alexa Fluor® 647 | sc-80015 AF647 | 200 µg/ml | $364.00 | |||
Rho G Antibody (1F3 B3 E5) Alexa Fluor® 680 | sc-80015 AF680 | 200 µg/ml | $364.00 | |||
Rho G Antibody (1F3 B3 E5) Alexa Fluor® 790 | sc-80015 AF790 | 200 µg/ml | $364.00 |