resistin Antibody (C-10): sc-376336
- resistin Antibody (C-10) is a mouse monoclonal IgG1 κ resistin antibody, cited in 14 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 37-71 within an internal region of resistin of human origin
- resistin Antibody (C-10) is recommended for detection of resistin of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-resistin Antibody (C-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for resistin Antibody (C-10) for WB and IHC(P) applications. These reagents are now offered in bundles with resistin Antibody (C-10) (see ordering information below).
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Resistin Antibody (C-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects resistin protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-resistin antibody (C-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Resistin, also known as adipose-derived secretory factor (ADSF), plays a crucial role in linking obesity to insulin resistance and diabetes, making resistin a significant target for research in metabolic disorders. Resistin is primarily secreted by adipose tissue and is characterized by a unique cysteine-rich structure, which includes a distinctive cysteine repeat motif essential for biological activity. This unique structure influences resistin′s interaction with other proteins and receptors, thereby modulating various signaling pathways involved in inflammation and metabolism. Resistin-like molecules, which share similar structural features, have been identified, with resistin-like α being predominantly expressed in adipose tissue and resistin-like β found in the gastrointestinal tract, particularly in the colon. Resistin-like β expression is notably elevated in proliferative epithelial cells and tumors, suggesting a potential role in intestinal proliferation and cancer biology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
resistin Antibody (C-10) References:
- Diabetes. The missing link with obesity? | Flier, JS. 2001. Nature. 409: 292-3. PMID: 11201721
- The hormone resistin links obesity to diabetes. | Steppan, CM., et al. 2001. Nature. 409: 307-12. PMID: 11201732
- A family of tissue-specific resistin-like molecules. | Steppan, CM., et al. 2001. Proc Natl Acad Sci U S A. 98: 502-6. PMID: 11209052
- A cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation. | Kim, KH., et al. 2001. J Biol Chem. 276: 11252-6. PMID: 11278254
- Regulation of fasted blood glucose by resistin. | Banerjee, RR., et al. 2004. Science. 303: 1195-8. PMID: 14976316
- The current biology of resistin. | Steppan, CM. and Lazar, MA. 2004. J Intern Med. 255: 439-47. PMID: 15049878
- Disulfide-dependent multimeric assembly of resistin family hormones. | Patel, SD., et al. 2004. Science. 304: 1154-8. PMID: 15155948
- Resistin, adiponectin, ghrelin, leptin, and proinflammatory cytokines: relationships in obesity. | Vendrell, J., et al. 2004. Obes Res. 12: 962-71. PMID: 15229336
- Resistin Resets Neutrophil Function in Kidney Diseases. | Schnellmann, R. 2016. Crit Care Med. 44: 1454-5. PMID: 27309176
- Human Resistin and Cardiovascular Disease. | Yuxiang, L. and Fujiu, K. 2020. Int Heart J. 61: 421-423. PMID: 32475957
- Resistin: An inflammatory cytokine with multi-faceted roles in cancer. | Sudan, SK., et al. 2020. Biochim Biophys Acta Rev Cancer. 1874: 188419. PMID: 32822824
- Resistin, a Novel Host Defense Peptide of Innate Immunity. | Li, Y., et al. 2021. Front Immunol. 12: 699807. PMID: 34220862
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
resistin Antibody (C-10) | sc-376336 | 200 µg/ml | $316.00 | |||
resistin Antibody (C-10): m-IgG Fc BP-HRP Bundle | sc-527524 | 200 µg Ab; 10 µg BP | $354.00 | |||
resistin Antibody (C-10): m-IgG1 BP-HRP Bundle | sc-532897 | 200 µg Ab; 20 µg BP | $354.00 | |||
resistin Antibody (C-10) AC | sc-376336 AC | 500 µg/ml, 25% agarose | $416.00 | |||
resistin Antibody (C-10) HRP | sc-376336 HRP | 200 µg/ml | $316.00 | |||
resistin Antibody (C-10) FITC | sc-376336 FITC | 200 µg/ml | $330.00 | |||
resistin Antibody (C-10) PE | sc-376336 PE | 200 µg/ml | $343.00 | |||
resistin Antibody (C-10) Alexa Fluor® 488 | sc-376336 AF488 | 200 µg/ml | $357.00 | |||
resistin Antibody (C-10) Alexa Fluor® 546 | sc-376336 AF546 | 200 µg/ml | $357.00 | |||
resistin Antibody (C-10) Alexa Fluor® 594 | sc-376336 AF594 | 200 µg/ml | $357.00 | |||
resistin Antibody (C-10) Alexa Fluor® 647 | sc-376336 AF647 | 200 µg/ml | $357.00 | |||
resistin Antibody (C-10) Alexa Fluor® 680 | sc-376336 AF680 | 200 µg/ml | $357.00 | |||
resistin Antibody (C-10) Alexa Fluor® 790 | sc-376336 AF790 | 200 µg/ml | $357.00 | |||
resistin (C-10) Neutralizing Peptide | sc-376336 P | 100 µg/0.5 ml | $68.00 |