Rak Antibody (H-12): sc-166478
- Rak Antibody (H-12) is a mouse monoclonal IgG2a κ Rak antibody, cited in 4 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 487-505 at the C-terminus of Rak of human origin
- Rak Antibody (H-12) is recommended for detection of Rak of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-Rak Antibody (H-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Rak Antibody (H-12) for WB and IHC(P) applications. These reagents are now offered in bundles with Rak Antibody (H-12) (see ordering information below).
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SEE ALSO...
Rak Antibody (H-12) is a mouse monoclonal IgG2a kappa light chain antibody that detects Rak protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Rak (H-12) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Rak protein, also known as GTK or PTK5, plays a crucial role in cellular signaling pathways, particularly in epithelial tissues, where Rak protein is involved in regulating processes such as cell growth, differentiation, and migration. Rak functions as a non-receptor tyrosine kinase, which is essential for the modulation of various cellular responses to external stimuli. The human Rak gene is located on chromosome 6q21-q22.3 and encodes a 505 amino acid protein that is specifically expressed in epithelial cells, highlighting Rak protein′s potential role in cancer biology and tissue homeostasis. By understanding the signaling pathways mediated by Rak protein, researchers can gain insights into Rak′s implications in tumorigenesis and other diseases, making anti-Rak antibody (H-12) a valuable tool for studying this important protein in various experimental contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Rak Antibody (H-12) References:
- Kinases of the Src family: structure and functions. | Tatosyan, AG. and Mizenina, OA. 2000. Biochemistry (Mosc). 65: 49-58. PMID: 10702640
- Src kinase-mediated signaling in leukocytes. | Korade-Mirnics, Z. and Corey, SJ. 2000. J Leukoc Biol. 68: 603-13. PMID: 11073097
- Selected glimpses into the activation and function of Src kinase. | Bjorge, JD., et al. 2000. Oncogene. 19: 5620-35. PMID: 11114743
- SRC family kinases mediate epithelial Na+ channel inhibition by endothelin. | Gilmore, ES., et al. 2001. J Biol Chem. 276: 42610-7. PMID: 11560932
- Isolation and chromosomal localization of the human fgr protooncogene, a distinct member of the tyrosine kinase gene family. | Tronick, SR., et al. 1985. Proc Natl Acad Sci U S A. 82: 6595-9. PMID: 2995972
- Insights into Src kinase functions: structural comparisons. | Williams, JC., et al. 1998. Trends Biochem Sci. 23: 179-84. PMID: 9612082
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rak Antibody (H-12) | sc-166478 | 200 µg/ml | $316.00 | |||
Rak Antibody (H-12): m-IgG Fc BP-HRP Bundle | sc-528977 | 200 µg Ab; 10 µg BP | $354.00 | |||
Rak Antibody (H-12): m-IgGκ BP-HRP Bundle | sc-521625 | 200 µg Ab, 40 µg BP | $354.00 | |||
Rak Antibody (H-12): m-IgG2a BP-HRP Bundle | sc-547221 | 200 µg Ab; 10 µg BP | $354.00 | |||
Rak Antibody (H-12) AC | sc-166478 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Rak Antibody (H-12) HRP | sc-166478 HRP | 200 µg/ml | $316.00 | |||
Rak Antibody (H-12) FITC | sc-166478 FITC | 200 µg/ml | $330.00 | |||
Rak Antibody (H-12) PE | sc-166478 PE | 200 µg/ml | $343.00 | |||
Rak Antibody (H-12) Alexa Fluor® 488 | sc-166478 AF488 | 200 µg/ml | $357.00 | |||
Rak Antibody (H-12) Alexa Fluor® 546 | sc-166478 AF546 | 200 µg/ml | $357.00 | |||
Rak Antibody (H-12) Alexa Fluor® 594 | sc-166478 AF594 | 200 µg/ml | $357.00 | |||
Rak Antibody (H-12) Alexa Fluor® 647 | sc-166478 AF647 | 200 µg/ml | $357.00 | |||
Rak Antibody (H-12) Alexa Fluor® 680 | sc-166478 AF680 | 200 µg/ml | $357.00 | |||
Rak Antibody (H-12) Alexa Fluor® 790 | sc-166478 AF790 | 200 µg/ml | $357.00 | |||
Rak (H-12) Neutralizing Peptide | sc-166478 P | 100 µg/0.5 ml | $68.00 |