Anti-Rae-1δ Antibody (Charlotte 1.23) is a mouse monoclonal IgG2a (kappa light chain) Rae-1δ antibody provided at 200 µg/ml
raised against Rae-1 delta-trasfected BAF cells of mouse origin
recommended for detection of Rae-1δ of mouse origin by FCM; non cross-reactive with Rae-1γ or other Balb/C Rae-1 molecules
available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Rae-1δ Antibody (Charlotte 1.23) for WB and IHC(P) applications. These reagents are now offered in bundles with Rae-1δ Antibody (Charlotte 1.23) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Rae-1δ Antibody (Charlotte 1.23) is a high quality monoclonal Rae-1 delta antibody (also designated Rae-1δ antibody) suitable for the detection of the Rae-1 delta protein of mouse origin. Rae-1δ Antibody (Charlotte 1.23) is available as both the non-conjugated anti-Rae-1 delta antibody form, as well as multiple conjugated forms of anti-Rae-1 delta antibody, including PE, FITC. Natural killer (NK) cells attack tumor and infected cells, but the receptors and ligands that stimulate them are poorly understood. Two murine ligands for the lectin-like receptor NKG2D, H60 and retinoic acid early inducible (Rae-1α, β, γ, δ and ε), are distant relatives of major histocompatibility complex class I molecules. These molecules are encoded by Rae-1 and H60 minor histocompatibility antigen genes on mouse chromosome 10 and show weak homology with MHC class I. Expression of the NKG2D ligands is low or absent on normal, adult tissues; however, they are constitutively expressed on some tumors and upregulated by retinoic acid. Ectopic expression of Rae-1 and H60 confers target susceptibility to NK cell attack. NKG2D binds to H60 with approximately 25-fold higher affinity than to Rae-1. Rae-1 and H60 compete directly for occupancy of NKG2D; therefore, NKG2-D can be occupied by only one ligand at a time. Additionally, Rae-1 and H60 ligands of the NKG2-D receptor stimulate tumor immunity.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
All trademarks are the property of their respective owners.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn