RADX Antibody (A-3): sc-514563
- RADX Antibody (A-3) is a mouse monoclonal IgG1 κ RADX antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1-23 at the N-terminus of RADX of human origin
- RADX Antibody (A-3) is recommended for detection of RADX of human origin by WB, IP, IF and ELISA
- Anti-RADX Antibody (A-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for RADX Antibody (A-3) for WB applications. These reagents are now offered in bundles with RADX Antibody (A-3) (see ordering information below).
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RADX Antibody (A-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects RADX protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RADX (A-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. RADX plays a crucial role in regulating DNA repair processes, particularly in response to replication stress, which is vital for maintaining genomic stability. By facilitating damaged DNA repair, RADX helps prevent mutations that could lead to cancer and other genetic disorders. RADX function is especially important in rapidly dividing cells, such as those in developing tissues or tumors, where DNA damage risk is heightened. Understanding RADX role in DNA repair mechanisms not only reveals fundamental cellular processes but also opens avenues for therapeutic interventions in cancer treatment, where targeting DNA repair pathways can enhance certain chemotherapeutic agents′ efficacy.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
RADX Antibody (A-3) References:
- Features of Turner's syndrome in women with polycystic ovaries. | Givens, JR., et al. 1975. Obstet Gynecol. 45: 619-24. PMID: 1143721
- Uncovering the complex mysteries of mosaicism. | Ozçelik, T. 2002. Nature. 417: 588. PMID: 12050634
- Overall DNA methylation and chromatin structure of normal and abnormal X chromosomes. | Bernardino-Sgherri, J., et al. 2002. Cytogenet Genome Res. 99: 85-91. PMID: 12900549
- Dystrophin and mutations: one gene, several proteins, multiple phenotypes. | Muntoni, F., et al. 2003. Lancet Neurol. 2: 731-40. PMID: 14636778
- The molecular basis of variation in human color vision. | Deeb, SS. 2005. Clin Genet. 67: 369-77. PMID: 15811001
- The metabolic syndrome is frequent in Klinefelter's syndrome and is associated with abdominal obesity and hypogonadism. | Bojesen, A., et al. 2006. Diabetes Care. 29: 1591-8. PMID: 16801584
- Novel form of a single X-linked visual pigment gene in a unique dichromatic color-vision defect. | Hayashi, T., et al. 2006. Vis Neurosci. 23: 411-7. PMID: 16961974
- Duodenal atresia in an infant with triple-X syndrome: a new associated malformation in 47,XXX. | Rolle, U., et al. 2007. Birth Defects Res A Clin Mol Teratol. 79: 612-3. PMID: 17469201
- Sensing X chromosome pairs before X inactivation via a novel X-pairing region of the Xic. | Augui, S., et al. 2007. Science. 318: 1632-6. PMID: 18063799
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RADX Antibody (A-3) | sc-514563 | 200 µg/ml | $316.00 | |||
RADX Antibody (A-3): m-IgG Fc BP-HRP Bundle | sc-531160 | 200 µg Ab; 10 µg BP | $354.00 | |||
RADX Antibody (A-3): m-IgGκ BP-HRP Bundle | sc-524770 | 200 µg Ab, 40 µg BP | $354.00 | |||
RADX Antibody (A-3): m-IgG1 BP-HRP Bundle | sc-544420 | 200 µg Ab; 20 µg BP | $354.00 | |||
RADX Antibody (A-3) AC | sc-514563 AC | 500 µg/ml, 25% agarose | $416.00 | |||
RADX Antibody (A-3) HRP | sc-514563 HRP | 200 µg/ml | $316.00 | |||
RADX Antibody (A-3) FITC | sc-514563 FITC | 200 µg/ml | $330.00 | |||
RADX Antibody (A-3) PE | sc-514563 PE | 200 µg/ml | $343.00 | |||
RADX Antibody (A-3) Alexa Fluor® 488 | sc-514563 AF488 | 200 µg/ml | $357.00 | |||
RADX Antibody (A-3) Alexa Fluor® 546 | sc-514563 AF546 | 200 µg/ml | $357.00 | |||
RADX Antibody (A-3) Alexa Fluor® 594 | sc-514563 AF594 | 200 µg/ml | $357.00 | |||
RADX Antibody (A-3) Alexa Fluor® 647 | sc-514563 AF647 | 200 µg/ml | $357.00 | |||
RADX Antibody (A-3) Alexa Fluor® 680 | sc-514563 AF680 | 200 µg/ml | $357.00 | |||
RADX Antibody (A-3) Alexa Fluor® 790 | sc-514563 AF790 | 200 µg/ml | $357.00 | |||
RADX (A-3) Neutralizing Peptide | sc-514563 P | 100 µg/0.5 ml | $68.00 |