Rad26L Antibody (B-11): sc-376609
- Rad26L Antibody (B-11) is a mouse monoclonal IgM κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 545-575 near the C-terminus of Rad26L of human origin
- recommended for detection of Rad26L isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and porcine
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Rad26L Antibody (B-11). This work is in progress.
Rad26L Antibody (B-11) is a mouse monoclonal IgM antibody that detects Rad26L in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Rad26L, also known as ERCC6L2, HEBO, BMFS2, SR278, or C9orf102, plays a pivotal role in DNA repair processes, particularly in repairing DNA double-strand breaks via homologous recombination repair pathway. Rad26L functions in maintaining genomic stability, which is crucial for preventing DNA damage accumulation that can lead to cancer and age-related diseases. Rad26L is located in the nucleus, where anti-Rad26L antibody (B-11) detects interactions with various proteins involved in DNA damage response, including RAD51 and BRCA1, which are essential for effective homologous recombination. Understanding Rad26L interactions with these proteins sheds light on DNA repair mechanisms and highlights potential therapeutic targets in diseases associated with genomic instability. Research into Rad26L′s role in cellular defense against DNA damage continues to advance our understanding of human health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rad26L Antibody (B-11) | sc-376609 | 200 µg/ml | $322.00 | |||
Rad26L (B-11) Neutralizing Peptide | sc-376609 P | 100 µg/0.5 ml | $69.00 |