Date published: 2025-10-19

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Rab 5A Antibody (A-12): sc-166622

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Datasheets
  • Rab 5A Antibody (A-12) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 177-211 within the C-terminus of Rab 5A of human origin
  • recommended for detection of Rab 5A of mouse, rat and human origin by WB, IP, IF and ELISA
  • See Rab 5 (D-11): sc-46692 for Rab 5A antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Rab 5A Antibody (A-12) for WB applications. These reagents are now offered in bundles with Rab 5A Antibody (A-12) (see ordering information below).

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Rab 5A Antibody (A-12) is a mouse monoclonal IgG1 antibody that detects Rab 5A in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Rab 5A plays a crucial role in the early stages of endocytosis and is essential for the regulation of vesicle trafficking within cells. Rab 5A is primarily located on early endosomes, where anti-Rab 5A antibody (A-12) can detect fusion of vesicles with these organelles, thereby ensuring proper sorting and delivery of internalized materials. Rab 5A′s location is integral to maintaining cellular homeostasis and responding to extracellular signals. Disruptions in Rab 5A function can lead to various cellular dysfunctions and are implicated in several diseases, including neurodegenerative disorders and cancer. Rab 5A monoclonal antibody (A-12) enables researchers to gain valuable insights into the dynamics of endosomal trafficking and the broader implications of Rab protein function in health and disease.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Rab 5A Antibody (A-12)

sc-166622
200 µg/ml
$316.00

Rab 5A Antibody (A-12): m-IgG Fc BP-HRP Bundle

sc-540131
200 µg Ab; 10 µg BP
$354.00

Rab 5A Antibody (A-12): m-IgG1 BP-HRP Bundle

sc-541922
200 µg Ab; 20 µg BP
$354.00

Rab 5A (A-12) Neutralizing Peptide

sc-166622 P
100 µg/0.5 ml
$68.00

Does this antibody also recognize RAB5b and/or RAB5c? Or, is the antibody ultra specfic for RAB5a?

Asked by: Edismauro
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2024-05-11

What application is the blocking peptide sc-166622 P appropriate for?

Asked by: Trav11
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_10, d_14, h_6CST
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Rated 5 out of 5 by from Signal via western blot analysis of Rab 5ASignal via western blot analysis of Rab 5A expression in non-transfected: sc-110760 and human Rab 5A transfected: sc-112278 293 whole cell lysates. -SCBT QC
Date published: 2015-04-19
Rated 5 out of 5 by from Signal via western blot analysis of Rab 5ASignal via western blot analysis of Rab 5A expression in non-transfected: sc-110760 and human Rab 5A transfected: sc-112278 293 whole cell lysates. -SCBT QC
Date published: 2015-02-14
Rated 5 out of 5 by from Signal via western blot analysis of Rab 5ASignal via western blot analysis of Rab 5A expression in HL-60 whole cell lysate. -SCBT QC
Date published: 2014-09-06
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Rab 5A Antibody (A-12) is rated 5.0 out of 5 by 3.
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