Rab 25 Antibody (D-7): sc-166144

Rab 25 Antibody (D-7) is a mouse monoclonal IgG1 antibody that detects Rab 25 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Rab 25, also known as CATX-8 or Rab 11c, is a member of the Rab family of proteins, which play a crucial role in intracellular transport processes, particularly in epithelial cells where Rab 25 is exclusively expressed. Rab 25 is essential for apical vesicle trafficking, facilitating the movement of carrier vesicles that transport newly synthesized proteins from the endoplasmic reticulum to the Golgi complex and ultimately to secretory vesicles. Proper functioning of Rab 25 is vital for maintaining cellular homeostasis and ensuring efficient protein transport, which is particularly important in cancer contexts, as Rab 25 is overexpressed in ovarian and breast cancer cells. Rab 25 overexpression has been linked to increased cell proliferation and tumor aggressiveness, highlighting Rab 25′s potential as a biomarker for cancer progression and a target for therapeutic intervention. Anti-Rab 25 antibody (D-7) provides a valuable tool for researchers investigating Rab 25′s role in various biological processes and disease states.

The preferred Rab 25 antibody is Rab 25 Antibody (3F12F3): sc-65978.