Rab 12 Antibody (H-11): sc-515613
- Rab 12 Antibody (H-11) is a mouse monoclonal IgG1 κ Rab 12 antibody provided at 200 µg/ml
- raised against amino acids 126-244 mapping at the C-terminus of Rab 12 of human origin
- Rab 12 Antibody (H-11) is recommended for detection of Rab 12 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Rab 12 Antibody (H-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Rab 12 Antibody (H-11) for WB applications. These reagents are now offered in bundles with Rab 12 Antibody (H-11) (see ordering information below).
Rab 12 Antibody (H-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects Rab 12 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Rab 12 (H-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Rab 12 protein, consisting of 244 amino acids, is primarily located on the membrane of the Golgi apparatus and is a member of the Rab family of GTPase proteins, which are crucial for intracellular transport processes. These proteins are essential for the movement of carrier vesicles that transport newly synthesized proteins from the endoplasmic reticulum to the Golgi complex and ultimately to secretory vesicles, highlighting their vital role in maintaining cellular function and homeostasis. Additionally, Rab proteins, including Rab 12, are integral to endocytic pathways, facilitating the uptake of extracellular materials and the recycling of membrane components. Proper functioning of Rab 12 is critical for efficient vesicular trafficking, and any dysregulation may lead to various cellular dysfunctions, making Rab 12 a significant target for research in cellular transport mechanisms and related diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Rab 12 Antibody (H-11) References:
- rab15, a novel low molecular weight GTP-binding protein specifically expressed in rat brain. | Elferink, LA., et al. 1992. J Biol Chem. 267: 5768-75. PMID: 1313420
- Transcriptome of pituitary adenylate cyclase-activating polypeptide-differentiated PC12 cells. | Ishido, M. and Masuo, Y. 2004. Regul Pept. 123: 15-21. PMID: 15518888
- Identification of rab12 as a vesicle-associated small GTPase highly expressed in Sertoli cells of rat testis. | Iida, H., et al. 2005. Mol Reprod Dev. 71: 178-85. PMID: 15791598
- The RSK factors of activating the Ras/MAPK signaling cascade. | Carriere, A., et al. 2008. Front Biosci. 13: 4258-75. PMID: 18508509
- Prospective of Ras signaling in stem cells. | Chakrabarty, K. and Heumann, R. 2008. Biol Chem. 389: 791-8. PMID: 18627319
- Molecular cloning and subcellular localization of three GTP-binding proteins of the rab subfamily. | Olkkonen, VM., et al. 1993. J Cell Sci. 106 (Pt 4): 1249-61. PMID: 8126105
- Identification of rab12 as a secretory granule-associated small GTP-binding protein in atrial myocytes. | Iida, H., et al. 1996. Circ Res. 78: 343-7. PMID: 8575079
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rab 12 Antibody (H-11) | sc-515613 | 200 µg/ml | $316.00 | |||
Rab 12 Antibody (H-11): m-IgG Fc BP-HRP Bundle | sc-531439 | 200 µg Ab; 10 µg BP | $354.00 | |||
Rab 12 Antibody (H-11): m-IgGκ BP-HRP Bundle | sc-525129 | 200 µg Ab, 40 µg BP | $354.00 | |||
Rab 12 Antibody (H-11): m-IgG1 BP-HRP Bundle | sc-544557 | 200 µg Ab; 20 µg BP | $354.00 | |||
Rab 12 Antibody (H-11) AC | sc-515613 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Rab 12 Antibody (H-11) HRP | sc-515613 HRP | 200 µg/ml | $316.00 | |||
Rab 12 Antibody (H-11) FITC | sc-515613 FITC | 200 µg/ml | $330.00 | |||
Rab 12 Antibody (H-11) PE | sc-515613 PE | 200 µg/ml | $343.00 | |||
Rab 12 Antibody (H-11) Alexa Fluor® 488 | sc-515613 AF488 | 200 µg/ml | $357.00 | |||
Rab 12 Antibody (H-11) Alexa Fluor® 546 | sc-515613 AF546 | 200 µg/ml | $357.00 | |||
Rab 12 Antibody (H-11) Alexa Fluor® 594 | sc-515613 AF594 | 200 µg/ml | $357.00 | |||
Rab 12 Antibody (H-11) Alexa Fluor® 647 | sc-515613 AF647 | 200 µg/ml | $357.00 | |||
Rab 12 Antibody (H-11) Alexa Fluor® 680 | sc-515613 AF680 | 200 µg/ml | $357.00 | |||
Rab 12 Antibody (H-11) Alexa Fluor® 790 | sc-515613 AF790 | 200 µg/ml | $357.00 |