QTRTD1 Antibody (G-5): sc-393480
- QTRTD1 Antibody (G-5) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 189-210 within an internal region of QTRTD1 of human origin
- recommended for detection of QTRTD1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine and porcine
- m-IgG3 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for QTRTD1 Antibody (G-5) for WB applications. These reagents are now offered in bundles with QTRTD1 Antibody (G-5) (see ordering information below).
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QTRTD1 Antibody (G-5) is a mouse monoclonal IgG3 antibody that detects QTRTD1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). QTRTD1, or queuine tRNA-ribosyltransferase domain containing 1, is a 415 amino acid protein crucial for tRNA modification and the biosynthesis of queuosine, a modified nucleoside that plays a significant role in the proper functioning of tRNA molecules. QTRTD1 is primarily located in the cytoplasm and the mitochondrial outer membrane, where QTRTD1 associates with QTRT1 to form an active queuine tRNA-ribosyltransferase complex. QTRTD1′s ability to exchange queuine for guanine at the wobble position of tRNAs with GUN anticodons is vital for maintaining the fidelity of protein synthesis, as queuosine modification enhances the stability and efficiency of tRNA. Furthermore, QTRTD1 is part of the queuine tRNA-ribosyltransferase family and is encoded by a gene located on human chromosome 3, which is associated with various genetic diseases, including Marfan Syndrome and von Hippel-Lindau syndrome. anti-QTRTD1 antibody (G-5) is an essential tool for researchers studying tRNA modifications and their implications in cellular processes and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
QTRTD1 Antibody (G-5) | sc-393480 | 200 µg/ml | $322.00 | |||
QTRTD1 Antibody (G-5): m-IgGκ BP-HRP Bundle | sc-535798 | 200 µg Ab; 40 µg BP | $361.00 | |||
QTRTD1 Antibody (G-5): m-IgG3 BP-HRP Bundle | sc-550312 | 200 µg Ab; 40 µg BP | $361.00 | |||
QTRTD1 (G-5) Neutralizing Peptide | sc-393480 P | 100 µg/0.5 ml | $69.00 |