PYGL Antibody (C3): sc-517597

PYGL Antibody (C3) is a mouse monoclonal IgG2a kappa light chain antibody that detects PYGL protein of mouse and rat origin by western blotting (WB). Anti-PYGL antibody (C3) is available as the non-conjugated form. PYGL (C3) antibody targets glycogen phosphorylase, which plays a crucial role in carbohydrate metabolism by catalyzing glycogen breakdown into glucose-1-phosphate, essential for energy production in cells. Glycogen phosphorylase functions prominently in liver and muscle tissues, helping regulate blood sugar levels and providing energy during fasting or intense exercise. Glycogen phosphorylase activity is controlled through allosteric regulation and covalent modifications, such as phosphorylation, enabling swift responses to energy demand changes. Due to significant involvement in glycogen metabolism, glycogen phosphorylase has emerged as a key target for developing therapeutic agents for conditions like type 2 diabetes mellitus, where dysregulation can trigger metabolic disorders.

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PYGL Antibody (C3) References:

1. Comparison of biochemical markers for the detection of minimal myocardial injury: superior sensitivity of cardiac troponin--T ELISA.  |  Lang, K., et al. 2000. J Intern Med. 247: 119-23. PMID: 10672139
2. Glycogen phosphorylase BB in acute coronary syndromes.  |  Peetz, D., et al. 2005. Clin Chem Lab Med. 43: 1351-8. PMID: 16309372
3. Effect of RecF protein on reactions catalyzed by RecA protein.  |  Madiraju, MV. and Clark, AJ. 1991. Nucleic Acids Res. 19: 6295-300. PMID: 1835535
4. rec genes and homologous recombination proteins in Escherichia coli.  |  Clark, AJ. 1991. Biochimie. 73: 523-32. PMID: 1911953
5. Can clonidine, enoximone, and enalaprilat help to protect the myocardium against ischaemia in cardiac surgery?  |  Boldt, J., et al. 1996. Heart. 76: 207-13. PMID: 8868976
6. Glycogen phosphorylase isoenzyme BB in diagnosis of myocardial ischaemic injury and infarction.  |  Krause, EG., et al. 1996. Mol Cell Biochem. 160-161: 289-95. PMID: 8901485
7. Progress in myocardial damage detection: new biochemical markers for clinicians.  |  Mair, J. 1997. Crit Rev Clin Lab Sci. 34: 1-66. PMID: 9055056
8. Glycogen phosphorylase isoenzyme BB to diagnose ischaemic myocardial damage.  |  Mair, J. 1998. Clin Chim Acta. 272: 79-86. PMID: 9581859

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-PYGL Antibody (C3) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-PYGL Antibody (C3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

PYGL Antibody (C3) Specifications

Alternate Product Name: PYGL

Product Clone Name: C3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids:

Epitope Target: PYGL

Epitope Species: rat

Product Reactivity/Detection: PYGL

Species Reactivity/Detection: mouse, rat

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide, 0.1% gelatin and 5% glycerol

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for PYGL Antibody (C3): N/A