PTPMT1 Antibody (B-12): sc-390947
- PTPMT1 Antibody (B-12) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 87-127 mapping within an internal region of PTPMT1 of human origin
- recommended for detection of PTPMT1 of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PTPMT1 Antibody (B-12) for WB and IHC(P) applications. These reagents are now offered in bundles with PTPMT1 Antibody (B-12) (see ordering information below).
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PTPMT1 Antibody (B-12) is a mouse monoclonal IgG2a antibody that detects PTPMT1 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PTPMT1, also known as MOSP or PLIP, is a crucial protein tyrosine phosphatase predominantly expressed in pancreatic β cells and localized to the matrix face of the inner mitochondrial membrane. This unique localization enables PTPMT1 to effectively dephosphorylate mitochondrial proteins, playing a significant role in ATP production and insulin secretion, which are essential processes for maintaining energy homeostasis and glucose regulation in the body. Notably, PTPMT1 exhibits a specific preference for the lipid signaling molecule phosphatidylinositol 5-phosphate (PI(5)P), highlighting PTPMT1′s importance in lipid metabolism and signaling pathways. Anti-PTPMT1 antibody (B-12) serves as an invaluable tool for researchers investigating the intricate roles of mitochondrial function and signaling in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PTPMT1 Antibody (B-12) | sc-390947 | 200 µg/ml | $322.00 | |||
PTPMT1 Antibody (B-12): m-IgGκ BP-HRP Bundle | sc-535666 | 200 µg Ab; 40 µg BP | $361.00 | |||
PTPMT1 Antibody (B-12): m-IgG2a BP-HRP Bundle | sc-546229 | 200 µg Ab; 10 µg BP | $361.00 |