PTD012 Antibody (E-3): sc-390408
- PTD012 Antibody (E-3) is a mouse monoclonal IgG2b κ PTD012 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 267-299 near the C-terminus of PTD012 of human origin
- PTD012 Antibody (E-3) is recommended for detection of PTD012 isoforms 1-4 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine
- Anti-PTD012 Antibody (E-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PTD012 Antibody (E-3) for WB and IHC(P) applications. These reagents are now offered in bundles with PTD012 Antibody (E-3) (see ordering information below).
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PTD012 Antibody (E-3) is a mouse monoclonal IgG2b kappa light chain antibody that detects PTD012 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). PTD012 (E-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PTD012 plays a crucial role in cellular signaling pathways, particularly in stress responses and cellular homeostasis. PTD012 (E-3) monoclonal antibody helps researchers understand PTD012′s involvement in regulating key processes such as apoptosis and cell cycle progression, which are vital for maintaining normal cellular function and preventing diseases like cancer. The gene encoding PTD012 is located on chromosome 11, a region known for its dense association with various genetic disorders, highlighting PTD012′s potential implications in both health and disease. PTD012 has been provisionally designated pending further characterization, and ongoing research aims to elucidate precise biological roles and interactions within the cell.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PTD012 Antibody (E-3) References:
- The 11q terminal deletion disorder: a prospective study of 110 cases. | Grossfeld, PD., et al. 2004. Am J Med Genet A. 129A: 51-61. PMID: 15266616
- Human chromosome 11 DNA sequence and analysis including novel gene identification. | Taylor, TD., et al. 2006. Nature. 440: 497-500. PMID: 16554811
- KCNQ1 K+ channel-mediated cardiac channelopathies. | Loussouarn, G., et al. 2006. Methods Mol Biol. 337: 167-83. PMID: 16929947
- Skipping of Exon 1 in the KCNQ1 gene causes Jervell and Lange-Nielsen syndrome. | Zehelein, J., et al. 2006. J Biol Chem. 281: 35397-403. PMID: 16987820
- Beta-thalassaemia and sickle cell anaemia as paradigms of hypercoagulability. | Ataga, KI., et al. 2007. Br J Haematol. 139: 3-13. PMID: 17854302
- The subcellular localization of the Niemann-Pick Type C proteins depends on the adaptor complex AP-3. | Berger, AC., et al. 2007. J Cell Sci. 120: 3640-52. PMID: 17895371
- Wilms tumour: prognostic factors, staging, therapy and late effects. | Kaste, SC., et al. 2008. Pediatr Radiol. 38: 2-17. PMID: 18026723
- Activation and regulation of ATM kinase activity in response to DNA double-strand breaks. | Lee, JH. and Paull, TT. 2007. Oncogene. 26: 7741-8. PMID: 18066086
- Targeted cancer therapies based on the inhibition of DNA strand break repair. | O'Connor, MJ., et al. 2007. Oncogene. 26: 7816-24. PMID: 18066095
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PTD012 Antibody (E-3) | sc-390408 | 200 µg/ml | $316.00 | |||
PTD012 Antibody (E-3): m-IgG Fc BP-HRP Bundle | sc-530147 | 200 µg Ab; 10 µg BP | $354.00 | |||
PTD012 Antibody (E-3): m-IgGκ BP-HRP Bundle | sc-523523 | 200 µg Ab, 40 µg BP | $354.00 | |||
PTD012 Antibody (E-3) AC | sc-390408 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PTD012 Antibody (E-3) HRP | sc-390408 HRP | 200 µg/ml | $316.00 | |||
PTD012 Antibody (E-3) FITC | sc-390408 FITC | 200 µg/ml | $330.00 | |||
PTD012 Antibody (E-3) PE | sc-390408 PE | 200 µg/ml | $343.00 | |||
PTD012 Antibody (E-3) Alexa Fluor® 488 | sc-390408 AF488 | 200 µg/ml | $357.00 | |||
PTD012 Antibody (E-3) Alexa Fluor® 546 | sc-390408 AF546 | 200 µg/ml | $357.00 | |||
PTD012 Antibody (E-3) Alexa Fluor® 594 | sc-390408 AF594 | 200 µg/ml | $357.00 | |||
PTD012 Antibody (E-3) Alexa Fluor® 647 | sc-390408 AF647 | 200 µg/ml | $357.00 | |||
PTD012 Antibody (E-3) Alexa Fluor® 680 | sc-390408 AF680 | 200 µg/ml | $357.00 | |||
PTD012 Antibody (E-3) Alexa Fluor® 790 | sc-390408 AF790 | 200 µg/ml | $357.00 | |||
PTD012 (E-3) Neutralizing Peptide | sc-390408 P | 100 µg/0.5 ml | $68.00 |