PSP94 Antibody (G-6): sc-377444
- PSP94 Antibody (G-6) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 1-113 representing full length PSP94 of rat origin
- Anti-PSP94 Antibody (G-6) is recommended for detection of PSP94 of mouse and rat origin by WB, IP, IF and ELISA
- Anti-PSP94 Antibody (G-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of PSP94 (G-6): sc-377444.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PSP94 Antibody (G-6). This work is in progress.
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SEE ALSO...
PSP94 Antibody (G-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects PSP94 of mouse and rat origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PSP94 Antibody (G-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Prostate secretory protein, or PSP94, is a 94 amino acid protein predominantly expressed in semen, playing crucial roles in both local and systemic functions within the reproductive tract. PSP94 is involved in the regulation of prostate health, and PSP94 levels are significantly altered in prostate cancer, a prevalent malignancy often linked to skeletal metastases that can lead to severe morbidity and mortality. PSP94′s ability to interact with specific proteins, such as the androgen receptor, highlights PSP94′s importance in modulating androgen signaling pathways, which are critical for prostate development and function. Elevated PSP94 levels may serve as a biomarker for certain sub-populations of low-stage and low-grade prostatic carcinoma, offering potential insights for targeted management and therapeutic strategies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PSP94 Antibody (G-6) References:
- Prostate secretory protein PSP-94 decreases tumor growth and hypercalcemia of malignancy in a syngenic in vivo model of prostate cancer. | Shukeir, N., et al. 2003. Cancer Res. 63: 2072-8. PMID: 12727822
- Two-site monoclonal antibody-based immunoradiometric assay for measuring prostate secretory protein in serum. | Huang, CL., et al. 1992. Clin Chem. 38: 817-23. PMID: 1375876
- A synthetic 15-mer peptide (PCK3145) derived from prostate secretory protein can reduce tumor growth, experimental skeletal metastases, and malignancy-associated hypercalcemia. | Shukeir, N., et al. 2004. Cancer Res. 64: 5370-7. PMID: 15289344
- Identification, purification and characterization of a novel human blood protein with binding affinity for prostate secretory protein of 94 amino acids. | Reeves, JR., et al. 2005. Biochem J. 385: 105-14. PMID: 15344909
- Increased intratumoral expression of prostate secretory protein of 94 amino acids predicts for worse disease recurrence and progression after radical prostatectomy in patients with prostate cancer. | Girvan, AR., et al. 2005. Urology. 65: 719-23. PMID: 15833515
- Prostate secretory protein of 94 amino acids (PSP-94) and its peptide (PCK3145) as potential therapeutic modalities for prostate cancer. | Shukeir, N., et al. 2005. Anticancer Drugs. 16: 1045-51. PMID: 16222145
- A novel serum marker, total prostate secretory protein of 94 amino acids, improves prostate cancer detection and helps identify high grade cancers at diagnosis. | Nam, RK., et al. 2006. J Urol. 175: 1291-7. PMID: 16515983
- Generation and characterization of monoclonal antibodies to prostate secretory protein. | Wright, GL., et al. 1990. Int J Cancer. 46: 39-49. PMID: 2194982
- Comparison of prostate secretory protein with prostate specific antigen and prostatic acid phosphatase as a serum biomarker for diagnosis and monitoring patients with prostate carcinoma. | Huang, CL., et al. 1993. Prostate. 23: 201-12. PMID: 7694265
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PSP94 Antibody (G-6) | sc-377444 | 200 µg/ml | $316.00 | |||
PSP94 Antibody (G-6) AC | sc-377444 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PSP94 Antibody (G-6) HRP | sc-377444 HRP | 200 µg/ml | $316.00 | |||
PSP94 Antibody (G-6) FITC | sc-377444 FITC | 200 µg/ml | $330.00 | |||
PSP94 Antibody (G-6) PE | sc-377444 PE | 200 µg/ml | $343.00 | |||
PSP94 Antibody (G-6) Alexa Fluor® 488 | sc-377444 AF488 | 200 µg/ml | $357.00 | |||
PSP94 Antibody (G-6) Alexa Fluor® 546 | sc-377444 AF546 | 200 µg/ml | $357.00 | |||
PSP94 Antibody (G-6) Alexa Fluor® 594 | sc-377444 AF594 | 200 µg/ml | $357.00 | |||
PSP94 Antibody (G-6) Alexa Fluor® 647 | sc-377444 AF647 | 200 µg/ml | $357.00 | |||
PSP94 Antibody (G-6) Alexa Fluor® 680 | sc-377444 AF680 | 200 µg/ml | $357.00 | |||
PSP94 Antibody (G-6) Alexa Fluor® 790 | sc-377444 AF790 | 200 µg/ml | $357.00 |