PSM Antibody (F-2): sc-514444
- PSM Antibody (F-2) is a mouse monoclonal IgG1 κ PSM antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 568-627 of PSM of human origin
- PSM Antibody (F-2) is recommended for detection of PSM of human origin by WB, IP, IF, IHC(P) and ELISA
- PSM Antibody (F-2) is available conjugated to agarose for IP; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PSM Antibody (F-2) for WB and IHC(P) applications. These reagents are now offered in bundles with PSM Antibody (F-2) (see ordering information below).
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SEE ALSO...
PSM Antibody (F-2) is a mouse monoclonal IgG1 kappa light chain antibody that detects PSM protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PSM (F-2) antibody is available in both non-conjugated and various conjugated forms, including agarose, phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Prostate-specific membrane antigen (PSM) plays a crucial role in prostate cancer diagnostics, as PSM is overexpressed in malignant tumors, making PSM a more reliable marker compared to other prostate-specific antigens like prostate-specific antigen (PSA), which can also be elevated in benign conditions. PSM is an integral membrane protein involved in cell signaling regulation and may influence tumor progression and metastasis. PSM expression is not only limited to prostate cancer but is also observed in other malignancies, highlighting PSM potential as a therapeutic target. PSM interaction with specific proteins in the tumor microenvironment is essential for understanding PSM role in cancer biology, as these interactions can affect tumor growth and response to treatment. Anti-PSM antibody (F-2) is an invaluable tool for researchers aiming to explore the complexities of prostate cancer and develop targeted therapies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PSM Antibody (F-2) References:
- STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors. | Hubert, RS., et al. 1999. Proc Natl Acad Sci U S A. 96: 14523-8. PMID: 10588738
- Tissue concentrations of prostate-specific antigen in prostatic carcinoma and benign prostatic hyperplasia. | Pretlow, TG., et al. 1991. Int J Cancer. 49: 645-9. PMID: 1718912
- Prostate-specific membrane antigen-targeted photoacoustic imaging of prostate cancer in vivo. | Zhang, HK., et al. 2018. J Biophotonics. 11: e201800021. PMID: 29653029
- Long-Circulating Prostate-Specific Membrane Antigen-Targeted NIR Phototheranostic Agent. | Overchuk, M., et al. 2020. Photochem Photobiol. 96: 718-724. PMID: 31742696
- Increased Prostate-Specific Membrane Antigen Uptake in Neurofibromatosis. | Wang, Y., et al. 2020. Clin Nucl Med. 45: 465-467. PMID: 32332318
- Prostate-specific membrane antigen expression in melanoma metastases. | Snow, H., et al. 2020. J Cutan Pathol. 47: 1115-1122. PMID: 32529651
- Expression of Prostate Specific Membrane Antigen (PSMA) in Breast Cancer. | Unger, C., et al. 2022. Geburtshilfe Frauenheilkd. 82: 50-58. PMID: 35027860
- Prostate-specific membrane antigen: evidence for the existence of a second related human gene. | Leek, J., et al. 1995. Br J Cancer. 72: 583-8. PMID: 7669565
- Molecular cloning of a complementary DNA encoding a prostate-specific membrane antigen. | Israeli, RS., et al. 1993. Cancer Res. 53: 227-30. PMID: 8417812
- Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family. | Su, ZZ., et al. 1996. Proc Natl Acad Sci U S A. 93: 7252-7. PMID: 8692978
- Two differentially expressed genes in normal human prostate tissue and in carcinoma. | Wang, FL., et al. 1996. Cancer Res. 56: 3634-7. PMID: 8705997
- Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer. | Reiter, RE., et al. 1998. Proc Natl Acad Sci U S A. 95: 1735-40. PMID: 9465086
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PSM Antibody (F-2) | sc-514444 | 200 µg/ml | $316.00 | |||
PSM Antibody (F-2): m-IgG Fc BP-HRP Bundle | sc-531129 | 200 µg Ab; 10 µg BP | $354.00 | |||
PSM Antibody (F-2): m-IgGκ BP-HRP Bundle | sc-524728 | 200 µg Ab, 40 µg BP | $354.00 | |||
PSM Antibody (F-2): m-IgG1 BP-HRP Bundle | sc-544410 | 200 µg Ab; 20 µg BP | $354.00 | |||
PSM Antibody (F-2) AC | sc-514444 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PSM Antibody (F-2) FITC | sc-514444 FITC | 200 µg/ml | $330.00 | |||
PSM Antibody (F-2) PE | sc-514444 PE | 200 µg/ml | $343.00 | |||
PSM Antibody (F-2) Alexa Fluor® 488 | sc-514444 AF488 | 200 µg/ml | $357.00 | |||
PSM Antibody (F-2) Alexa Fluor® 546 | sc-514444 AF546 | 200 µg/ml | $357.00 | |||
PSM Antibody (F-2) Alexa Fluor® 594 | sc-514444 AF594 | 200 µg/ml | $357.00 | |||
PSM Antibody (F-2) Alexa Fluor® 647 | sc-514444 AF647 | 200 µg/ml | $357.00 | |||
PSM Antibody (F-2) Alexa Fluor® 680 | sc-514444 AF680 | 200 µg/ml | $357.00 | |||
PSM Antibody (F-2) Alexa Fluor® 790 | sc-514444 AF790 | 200 µg/ml | $357.00 |